Functional hydrogels for treatment of chronic wounds

I Firlar, M Altunbek, C McCarthy, M Ramalingam… - Gels, 2022 - mdpi.com
Chronic wounds severely affect 1–2% of the population in developed countries. It has been
reported that nearly 6.5 million people in the United States suffer from at least one chronic …

Immunomodulatory hydrogels: advanced regenerative tools for diabetic foot ulcer

Y Xiong, Q Feng, L Lu, K Zha, T Yu, Z Lin… - Advanced Functional …, 2023 - Wiley Online Library
Diabetic foot ulcer (DFU) is one of the most common complications of diabetes, bringing
physical and mental challenges for patients due to the lack of efficient curative therapy …

Flexible bicolorimetric polyacrylamide/chitosan hydrogels for smart real‐time monitoring and promotion of wound healing

K Zheng, Y Tong, S Zhang, R He, L Xiao… - Advanced Functional …, 2021 - Wiley Online Library
Real‐time monitoring of wound healing remains a major challenge in clinical tissue
regeneration, calling the need for the development of biomaterial‐guided on‐site monitoring …

Advances in ultrasound-responsive hydrogels for biomedical applications

Y Zhou, G Liu, S Guo - Journal of Materials Chemistry B, 2022 - pubs.rsc.org
Various intelligent hydrogels have been developed for biomedical applications because
they can achieve multiple, variable, controllable and reversible changes in their shape and …

Degradable hydrogels: Design mechanisms and versatile applications

B Hosseinzadeh, M Ahmadi - Materials Today Sustainability, 2023 - Elsevier
Recent environmental issues raised by the durability of polymers call for designing
degradable products. Hydrogels with widespread applications in superabsorbent and …

Experimental and Theoretical Exploration of the Kinetics and Thermodynamics of the Nucleophile-Induced Fragmentation of Ylidenenorbornadiene Carboxylates

AD Richardson, SJ L'Heureux, AM Henry… - The Journal of …, 2023 - ACS Publications
Ylidenenorbornadienes (YNDs), prepared by [4+ 2] cycloadditions between fulvenes and
acetylene carboxylates, react with thiol nucleophiles to yield mixtures of four to eight …

Emerging trends in the application of hydrogel-based biomaterials for enhanced wound healing: A literature review

P Wang, F Cai, Y Li, X Yang, R Feng, H Lu, X Bai… - International Journal of …, 2024 - Elsevier
Currently, there is a rising global incidence of diverse acute and chronic wounds,
underscoring the immediate necessity for research and treatment advancements in wound …

Facile Preparation of Carbohydrate‐Containing Adjuvants Based on Self‐Assembling Glycopeptide Conjugates

B Wang, S Liu, H Li, W Dong, H Liu… - Angewandte Chemie …, 2024 - Wiley Online Library
Carbohydrates are intriguing biomolecules possessing diverse biological activities,
including immune stimulating capability. However, their biomedical applications have been …

Experimental and Theoretical Analysis of the Thiol-Promoted Fragmentation of 2-Halo-3-tosyl-oxanorbornadienes

M Carranza, AT Carmona, CD Navo, I Robina… - Organic …, 2023 - ACS Publications
2-Halo-3-tosyl-oxanorbornadienes are able to accept two thiol molecules through an initial
nucleophilic substitution, giving isolable oxabicyclic thiovinyl sulfones that, subsequently …

The influence of substitution on thiol-induced oxanorbornadiene fragmentation

L De Pascalis, MK Yau, D Svatunek, Z Tan… - Organic …, 2021 - ACS Publications
Oxanorbornadienes (ONDs) undergo facile Michael addition with thiols and then fragment
by a retro-Diels–Alder (rDA) reaction, a unique two-step sequence among electrophilic …