NLRP3 inflammasome is a multiprotein complex involved in host immune response─ which
exerts various biological effects by mediating the maturation and secretion of IL-1β and IL …

Nod-like receptor protein 3 (NLRP3), a therapeutic target that has a close relationship with
inflammatory diseases, has drawn significant attention from researchers in the field. An …

The NLRP3 inflammasome is a component of the innate immune system involved in the
production of proinflammatory cytokines. Neurodegenerative disorders, including …

The NLRP3 inflammasome is a critical component of innate immunity that senses diverse
pathogen-and host-derived molecules. However, its aberrant activation has been associated …

NLRP3 is an intracellular sensor protein that causes inflammasome formation and
pyroptosis in response to a wide range of stimuli. Aberrant activation of NLRP3 …

NLRP3 is a molecular sensor recognizing a wide range of danger signals. Its activation
leads to the assembly of an inflammasome that allows for activation of caspase-1 and …

As a key regulator of the innate immune system, the NLRP3 inflammasome responds to a
variety of environmental insults through activation of caspase-1 and release of the …

Inappropriate and chronic activation of the cytosolic NOD‐, LRR‐, and pyrin domain‐
containing 3 (NLRP3) inflammasome, a key component of innate immunity, likely underlies …

Atherosclerosis, a chronic inflammatory disease characterized by arterial plaque
accumulation, remains a significant global health challenge. In recent years …

The NLRP3 inflammasome is an intracellular, multiprotein complex that promotes the auto-
catalytic activation of caspase-1 and the subsequent maturation and secretion of the pro …