MicroRNAs (miRNAs) are small regulatory molecules post-transcriptionally suppressing
mRNA activity. Many miRNAs in various organisms have been cloned but many unknown …

Background Net survival rates of cancer are increasing worldwide, placing a strain on health
service provision. There is a drive to transfer the care of cancer survivors—individuals living …

Background In this article we outline Burden of Treatment Theory, a new model of the
relationship between sick people, their social networks, and healthcare services. Health …

Background: Despite potential harm that can result from polypharmacy, real-world data on
polypharmacy in the setting of heart failure (HF) are limited. We sought to address this …

Objective To explore medication-related burden (MRB) and patients' lived experience with
medicines (PLEM) without regard to particular medication therapies or medical conditions …

Across the world healthcare systems are struggling to cope with increasing demands and
costs. Rising life expectancy has been accompanied by an explosion in the prevalence of …

Objective To develop and validate a new scale to assess treatment burden (the effort of
looking after one's health) for patients with multimorbidity. Design Mixed-methods. Setting …

Background Management strategies for patients with chronic conditions are becoming
increasingly complex, which may result in a burden of treatment for patients. To develop a …

Aims and objectives To explore chronic heart failure patients' perceptions of the burden
related to treatment and self‐care. Background Living with chronic heart failure entails …

Treatment burden should be included in clinical practice guidelines Page 1 Treatment burden
should be included in clinical practice guidelines Claudia Dobler and colleagues argue that …