Identification of altered exosomal microRNAs and mRNAs in Alzheimer's disease

L Su, R Li, Z Zhang, J Liu, J Du, H Wei - Ageing Research Reviews, 2022 - Elsevier
Alzheimer's disease (AD) is a progressive neurodegenerative disease characterized by
decreased memory and cognitive functions. Exosomes carry a variety of important …

[HTML][HTML] The neurobiology of non-coding RNAs and Alzheimer's disease pathogenesis: Pathways, mechanisms and translational opportunities

E Lauretti, K Dabrowski, D Praticò - Ageing Research Reviews, 2021 - Elsevier
In the past two decades, advances in sequencing technology and analysis of the human and
mouse genome have led to the discovery of many non-protein-coding RNAs (ncRNAs) …

Identification of potential key genes associated with the pathogenesis and prognosis of gastric cancer based on integrated bioinformatics analysis

X Liu, J Wu, D Zhang, Z Bing, J Tian, M Ni… - Frontiers in …, 2018 - frontiersin.org
Background and Objective: Despite striking advances in multimodality management, gastric
cancer (GC) remains the third cause of cancer mortality globally and identifying novel …

MicroRNAs from plants to animals, do they define a new messenger for communication?

Z Li, R Xu, N Li - Nutrition & metabolism, 2018 - Springer
MicroRNAs (miRNAs), a class of single-stranded non-coding RNA of about 22 nucleotides,
are potent regulators of gene expression existing in both plants and animals. Recent studies …

Alzheimer's disease large-scale gene expression portrait identifies exercise as the top theoretical treatment

MA Hill, SC Gammie - Scientific reports, 2022 - nature.com
Alzheimer's disease (AD) is a complex neurodegenerative disorder that affects multiple
brain regions and is difficult to treat. In this study we used 22 AD large-scale gene …

microRNA-based biomarkers in Alzheimer's disease (AD)

Y Zhao, V Jaber, PN Alexandrov, A Vergallo… - Frontiers in …, 2020 - frontiersin.org
Alzheimer's disease (AD) is a multifactorial, age-related neurological disease characterized
by complex pathophysiological dynamics taking place at multiple biological levels, including …

Profiling of serum exosome MiRNA reveals the potential of a MiRNA panel as diagnostic biomarker for Alzheimer's disease

Z Dong, H Gu, Q Guo, S Liang, J Xue, F Yao, X Liu… - Molecular …, 2021 - Springer
Alzheimer's disease (AD) is the most common neurodegenerative disease in the older
adults. Although much effort has been made in the analyses of diagnostic biomarkers, such …

A review on omics-based biomarkers discovery for Alzheimer's disease from the bioinformatics perspectives: statistical approach vs machine learning approach

MS Tan, PL Cheah, AV Chin, LM Looi… - Computers in biology and …, 2021 - Elsevier
Alzheimer's Disease (AD) is a neurodegenerative disease that affects cognition and is the
most common cause of dementia in the elderly. As the number of elderly individuals …

Microglia specific deletion of miR-155 in Alzheimer's disease mouse models reduces amyloid-β pathology but causes hyperexcitability and seizures

MS Aloi, KE Prater, REA Sánchez, A Beck… - Journal of …, 2023 - Springer
Alzheimer's Disease (AD) is characterized by the accumulation of extracellular amyloid-β
(Aβ) as well as CNS and systemic inflammation. Microglia, the myeloid cells resident in the …

Diagnosis and management of neuropsychiatric symptoms in Alzheimer's disease

D Wolinsky, K Drake, J Bostwick - Current psychiatry reports, 2018 - Springer
Abstract Purpose of Review To explore the most recent developments in the effective
diagnosis and treatment of neuropsychiatric symptoms (NPS) in Alzheimer's disease (AD) …