Weight loss is difficult to achieve and maintaining the weight loss is an even greater
challenge. The identification of factors associated with weight loss maintenance can …

The results of exercise programmes designed to reduce body fat are disappointing.
However, the reporting of weight loss as mean values disguises those individuals who do …

Aims: To review the major trials that evaluated the efficacy and safety of the use of
sibutramine for weight loss and the impact of this agent on obesity-related disorders …

We used functional magnetic resonance imaging to explore brain responses to food images
in overweight humans, examining independently the impact of a prescan meal (“satiety”) …

Background: Obesity has become a global epidemic with recent estimates of> 400 million
obese adults. Despite this, there are few safe and effective pharmacological interventions for …

Overweight and obesity, if sustained, are serious medical problems reaching an epidemic
proportion. It is estimated that over 55% of the adult population is affected by overweight and …

Objective The objective of the study was to evaluate whether sibutramine and rimonabant,
drugs that decrease food intake in human and non-human animals, affect the discriminative …

Background: Obesity treatment with single drugs produces weight losses of about 8–10% of
initial body weight. Few studies of combinations of drugs for treating obesity have been …

There is substantial evidence from cellular, animal and epidemiological studies in support of
a role for calcium, and in particular, dairy foods in the regulation of weight (McCarron, 1983; …

The use of pharmacologic agents for treatment of obesity has a checkered history. A variety
of drugs and hormones have been shown to cause short-term weight loss in obese adults; …