Extracellular vesicles as tools and targets in therapy for diseases
Extracellular vesicles (EVs) are nano-sized, membranous structures secreted into the
extracellular space. They exhibit diverse sizes, contents, and surface markers and are …
extracellular space. They exhibit diverse sizes, contents, and surface markers and are …
Potential clinical utility of liquid biopsies in ovarian cancer
JW Zhu, P Charkhchi, MR Akbari - Molecular cancer, 2022 - Springer
Background Ovarian cancer (OC) is the most lethal gynecologic malignancy worldwide. One
of the main challenges in the management of OC is the late clinical presentation of disease …
of the main challenges in the management of OC is the late clinical presentation of disease …
Extracellular vesicle quantification and characterization: common methods and emerging approaches
TA Hartjes, S Mytnyk, GW Jenster, V van Steijn… - Bioengineering, 2019 - mdpi.com
Extracellular vesicles (EVs) are a family of small membrane vesicles that carry information
about cells by which they are secreted. Growing interest in the role of EVs in intercellular …
about cells by which they are secreted. Growing interest in the role of EVs in intercellular …
Extracellular vesicle isolation and characterization: toward clinical application
Two broad categories of extracellular vesicles (EVs), exosomes and shed microvesicles
(sMVs), which differ in size distribution as well as protein and RNA profiles, have been …
(sMVs), which differ in size distribution as well as protein and RNA profiles, have been …
Role of exosomal proteins in cancer diagnosis
W Li, C Li, T Zhou, X Liu, X Liu, X Li, D Chen - Molecular cancer, 2017 - Springer
Exosomes are emerging as a new type of cancer biomarkers. Exosome is a bilayered nano-
sized vesicle secreted by various living cells in all body fluids. Based on the expanding …
sized vesicle secreted by various living cells in all body fluids. Based on the expanding …
Tumor-derived exosomes and their role in cancer progression
TL Whiteside - Advances in clinical chemistry, 2016 - Elsevier
Tumor cells actively produce, release, and utilize exosomes to promote tumor growth.
Mechanisms through which tumor-derived exosomes subserve the tumor are under intense …
Mechanisms through which tumor-derived exosomes subserve the tumor are under intense …
Exosomes in cancer diagnostics
YH Soung, S Ford, V Zhang, J Chung - Cancers, 2017 - mdpi.com
Exosomes are endosome derived extracellular vesicles of 30–120 nm size ranges.
Exosomes have been identified as mediators of cell-to-cell communication by transferring …
Exosomes have been identified as mediators of cell-to-cell communication by transferring …
Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts
Exosomes derived from solid tumor cells are involved in immune suppression,
angiogenesis, and metastasis, but the role of leukemia-derived exosomes has been less …
angiogenesis, and metastasis, but the role of leukemia-derived exosomes has been less …
Recent progress in detection and profiling of cancer cell‐derived exosomes
H Xiong, Z Huang, Z Yang, Q Lin, B Yang, X Fang… - Small, 2021 - Wiley Online Library
Exosomes, known as nanometer‐sized vesicles (30–200 nm), are secreted by many types of
cells. Cancer‐derived exosomes have great potential to be biomarkers for early clinical …
cells. Cancer‐derived exosomes have great potential to be biomarkers for early clinical …
Evidence-based clinical use of nanoscale extracellular vesicles in nanomedicine
Recent research has demonstrated that all body fluids assessed contain substantial
amounts of vesicles that range in size from 30 to 1000 nm and that are surrounded by …
amounts of vesicles that range in size from 30 to 1000 nm and that are surrounded by …