The mucosal lining of the gut has co-evolved with a diverse microbiota over millions of
years, leading to the development of specialized mechanisms to actively limit the invasion of …

The immune system probably evolved to limit the negative effects exerted by pathogens on
host homeostasis. This defence strategy relies on the concerted action of innate and …

Little is known about the regulatory effect of microbiota on the proliferation and regeneration
of ISCs. Here, we found that L. reuteri stimulated the proliferation of intestinal epithelia by …

Scope: The proliferation and differentiation of intestinal stem cells (ISCs) are the basis of
intestinal renewal and regeneration, and gut microbiota plays an important role in it. Dietary …

Over a long period of evolution, insects have developed unique intestinal defenses against
invasion by foreign microorganisms, including physical defenses and immune responses …

The insect midgut epithelium represents an interface between the internal and the external
environment and it is the almost unique epithelial tissue by which these arthropods acquire …

Drosophila suzukii Matsumura is an invasive species of vinegar fly that has become a
prominent pest of berries and other soft-skinned fruits. Unlike most other Drosophila species …

In all metazoans, the intestinal tract is an essential organ to integrate nutritional signaling,
hormonal cues and immunometabolic networks. The dysregulation of intestinal epithelium …

Environmental stresses experienced during development exert many long-term effects upon
health and disease. For example, chemical oxidants or genetic perturbations that induce low …

The gut is the primary interface between an animal and food, but how it adapts to qualitative
dietary variation is poorly defined. We find that the Drosophila midgut plastically resizes …