With the advent of effective tools to study lipids, including mass spectrometry-based
lipidomics, lipids are emerging as central players in cancer biology. Lipids function as …

Accumulating evidence shows that deregulation of fatty acid (FA) metabolism is associated
with the development of cancer. Long-chain acyl-coenzyme A synthases (ACSLs) are …

Cancer cells are highly dependent on different metabolic pathways for sustaining their
survival, growth, and proliferation. Lipid metabolism not only provides the energetic needs of …

A number of studies have shown that aspirin, as commonly prescribed drug, prevents the
development of hepatocellular carcinoma (HCC). Ferroptosis as a dynamic tumor …

Transcatheter arterial chemoembolization (TACE) is widely used for the treatment of
advanced hepatocellular carcinoma (HCC). However, the long-term hypoxic …

Simple Summary The application of non-steroidal anti-inflammatory drugs (NSAIDs) in
cancer therapy has been a widely studied topic for almost four decades. This review …

Preclinical and clinical studies provide evidence for aspirin as a preventative agent for
cancer. Compelling direct evidence supports a chemopreventive effect of aspirin in …

Abnormal lipid metabolism plays crucial roles in the development of cancer. Spindlin 1
(SPIN1) involving the process of spindle organization and chromosomal stability serves as …

Murine hepatitis virus strain A59 (MHV-A59) was shown to induce pyroptosis, apoptosis, and
necroptosis of infected cells, especially in the murine macrophages. However, whether …

Background & Aims Aspirin therapy has been associated with reduced risk of colon cancer,
but there is only limited evidence for its effects on risk of hepatitis C virus (HCV)-related …