In multicellular organisms, Wnt proteins govern stem and progenitor cell renewal and
differentiation to regulate embryonic development, adult tissue homeostasis and tissue …

Background The fast-expanding global population, coupled with the threat of climate
change, have led to fresh challenges in meeting nutritional security. As a response to this …

Background Wnt/β-catenin signaling is critical for lung development and AT2 stem cell
maintenance in adults, but excessive pathway activation has been associated with …

WNT signaling is crucial for embryonic development, and adult tissue homeostasis and
regeneration, through its essential roles in cell fate, patterning, and stem cell regulation. The …

The Wnt signaling pathway is a huge network governing development and homeostasis,
dysregulation of which is associated with a myriad of human diseases. The Frizzled receptor …

The emergence of antibody based surrogate WNT molecules has revolutionized research
exploiting organoid cultures. In this issue of Cell Chemical Biology, Post et al. 1 present a …

Pharmacological modulation of the Wnt/β-catenin signaling pathway holds promises for both
basic research and therapeutic applications. In this issue of Cell Chemical Biology …