Cardiopulmonary bypass perfusion management significantly affects postoperative
outcomes. In recent years, the principles of goal-directed therapy have been applied to the …

Neonates possess a molecular variant of fibrinogen, known as fetal fibrinogen,
characterized by increased sialic acid, a greater negative charge, and decreased activity …

Aim. The study aims to describe the long‐term cardiological and psychological results of our
first surgical cohort of arterial switch operation (ASO) patients and compare the results with …

In children with congenital heart disease (CHD), pulmonary blood flow (Qp) contributes to
alterations of pulmonary mechanics and gas exchange, while cardiopulmonary bypass …

Recent advances in perioperative management of adult and pediatric patients requiring
open heart surgery (OHS) and cardiopulmonary bypass (CPB) for cardiac and/or congenital …

OBJECTIVES: Improved congenital heart defect (CHD) operations have reduced operative
mortality to 3%. The major concern is now long-term neurological outcomes. We measured …

Background Univentricular congenital heart defects require open-heart surgery soon after
birth, and are associated with risk of brain injury and poor neurologic outcome. Methods This …

OBJECTIVES Detailed anatomical information is essential for planning of surgical therapy in
patients with congenital heart disease. We wanted to determine whether cinematic …

Methylprednisolone is used in neonates to modulate cardiopulmonary bypass (CPB)–
induced inflammation, but optimal dosing and exposure are unknown. We used plasma …

Newborns with congenital heart disease undergoing cardiac surgery are at risk of
neurodevelopmental impairment with limited understanding of the impact of intra‐operative …