The COVID-19 pandemic has highlighted the importance in the understanding of the biology
of SARS-CoV-2. After more than two years since the first report of COVID-19, it remains …

Coronaviruses (CoVs) are a family of the largest RNA viruses that typically cause
respiratory, enteric, and hepatic diseases in animals and humans, imposing great threats to …

Coronaviruses rely on host proteases to activate the viral spike protein, which facilitates
fusion with the host cell membrane and the release of viral genomic RNAs into the host cell …

Drug repurposing is a promising approach towards the discovery of novel treatments against
Neglected Tropical Diseases, such as Leishmaniases, presenting the advantage of reducing …

Human coronaviruses (hCoVs) infect millions of people every year. Among these, MERS,
SARS-CoV-1, and SARS-CoV-2 caused significant morbidity and mortality and their …

The COVID‐19 pandemic continues to pose a substantial threat to human lives and is likely
to do so for years to come. Despite the availability of vaccines, searching for efficient small …

Coxsackievirus A16 (CA16) belongs to the Human Enterovirus A species, which is a
common pathogen causing hand, foot, and mouth disease in children. Currently, specific …

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus continues to
cause severe disease and deaths in many parts of the world, despite massive vaccination …

The outbreak of coronavirus disease 2019 (COVID‐19) pandemic caused by the severe
acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) is a global threat to human health …

Coronaviruses rely on the viral-encoded chymotrypsin-like main protease (Mpro or 3CLpro)
for replication and assembly. Our previous research on Mpro of SARS-CoV-2 identified …