A vast literature strongly suggests that the endocannabinoid (eCB) system and related
bioactive lipids (the paracannabinoid system) contribute to numerous physiological …

The discovery of the endocannabinoidome (eCBome) is evolving gradually with yet to be
elucidated functional lipid mediators and receptors. The diet modulates these bioactive …

3, 5, 6, 7, 8, 3′, 4′-Heptamethoxyflavone (HMF) could prevent obesity and hyperlipidemia,
but its effects on gut microbiota and fecal metabolites remain unclear. Here, the effect of …

Background The present study aimed to assess the therapeutic effects of boron citrate and
oleoylethanolamide supplementation in patients with COVID-19. Methods Forty adult …

Background: Oxidative stress is considered a major factor in the pathophysiology of non-
alcoholic liver disease (NAFLD). A growing body of evidence indicates that …

Arachidonic acid (AA) is a key precursor for proinflammatory and anti‐inflammatory
derivatives that regulate the inflammatory response. The modulation of AA metabolism is a …

Background Human mesenchymal stem/stromal cells (hMSCs) are known for their
pronounced therapeutic potential; however, they are still applied in limited clinical cases for …

Endoplasmic reticulum stress (ERS) is closely associated with the occurrence and
development of many liver diseases. ERS models mostly include experimental animals such …

Introduction: Previous work suggests the existence of a paracrine signaling mechanism in
which histamine released from visceral mast cells into the portal circulation contributes to …

Unhealthy lifestyle habits including a sedentary life, the lack of physical activity, and wrong
dietary habits are the major ones responsible for the constant increase of obesity and …