Gastric cancer (GC) is globally the fifth most common cancer and third leading cause of
cancer death. A complex disease arising from the interaction of environmental and host …

Methodological breakthroughs over the past four decades have repeatedly revolutionized
transcriptome profiling. Using RNA sequencing (RNA-seq), it has now become possible to …

Gastric cancer, a leading cause of cancer-related deaths, is a heterogeneous disease. We
aim to establish clinically relevant molecular subtypes that would encompass this …

Gastric cancer is among the most common malignancies worldwide, characterized by
geographical, epidemiological and histological heterogeneity. Here, we report an extensive …

Gastric cancer is diagnosed in nearly one million new patients each year and it remains the
second leading cause of cancer-related deaths worldwide. Although gastric cancer …

Alternative usage of transcript isoforms from the same gene has been hypothesized as an
important feature in cancers. However, differential usage of gene transcripts between …

Background Deregulated gene expression is a hallmark of cancer; however, most studies to
date have analyzed short-read RNA sequencing data with inherent limitations. Here, we …

Signet-ring cell carcinoma (SRCC) has specific epidemiology and oncogenesis in gastric
cancer, however, with no systematical investigation for prognostic genomic features. Here …

Aging is associated with DNA accumulation and increased homeostatic proliferation of
circulating T cells. Although these attributes are associated with aging-related autoimmunity …

Gastric cancer is the fifth most incident and the third most common cause of cancer-related
death in the world. Infection with Helicobacter pylori is the major risk factor for this disease …