Microtubules are appealing as intracellular targets for anticancer activity due to their
importance in cell division. Three important binding sites are present on the tubulin protein …

Introduction Microtubules play a vital role in cancer therapeutics. They are implicated in
tumorigenesis, thus inhibiting tubulin polymerization in cancer cells, and have now become …

Pseudo‐homogeneous polymeric photocatalysts are an emerging class of highly efficient
and tunable photocatalytic materials, where the photocatalytic centers are easily accessible …

Diazoacetates are widely used to synthesize highly valuable indoles. Previous research has
focused on using metal carbene reactivity or the innate nucleophilicity of the diazoacetates …

Millepachine, a bioactive natural product isolated from the seeds of Millettia pachycarpa, is
reported to display potential antitumor activity. In this study, novel indole-containing hybrids …

A conceptually novel approach for the modular and divergent synthesis of highly
functionalized indoles via trifluoroacetic acid-promoted amino-Claisen rearrangement is …

Simultaneous inhibition of tumor vasculature and the glycolysis pathway may be a targeted
anti-tumor strategy to inhibit tumor nutrient supply. Flavonoids are natural products with …

Chalcones have the characteristics of simple structure, easy synthesis and potent anti-tumor
activity. Herein, a small library of fifty-five novel indole-chalcone derivatives were rationally …

Herein, we described the synthesis of indole-tetrazole coupled aromatic amides (6a-o) and
evaluated their in vitro anticancer activity. Some of the compounds namely N-(4 …

A series of new 1, 2, 4-triazolo-linked bis-indolyl conjugates (15a–r) were prepared by
multistep synthesis and evaluated for their cytotoxic activity against various human cancer …