Synthesis and initial biological evaluation of new mimics of the LXR-modulator 22 (S)-hydroxycholesterol

OAH Åstrand, M Sandberg, I Sylte, CH Görbitz… - Bioorganic & Medicinal …, 2014 - Elsevier
The generic, synthetic oxysterol 22 (S)-hydroxycholesterol (22SHC) has shown antagonistic
effects towards liver X receptor (LXR) in vitro and promising effects on plasma triacylglycerol …