Direct Cell Radiolabeling for in Vivo Cell Tracking with PET and SPECT Imaging

PJ Gawne, F Man, PJ Blower… - Chemical reviews, 2022 - ACS Publications
The arrival of cell-based therapies is a revolution in medicine. However, its safe clinical
application in a rational manner depends on reliable, clinically applicable methods for …

State of the art of 18F-FDG PET/CT application in inflammation and infection: a guide for image acquisition and interpretation

M Casali, C Lauri, C Altini, F Bertagna… - Clinical and …, 2021 - Springer
Aim The diagnosis, severity and extent of a sterile inflammation or a septic infection could be
challenging since there is not one single test able to achieve an accurate diagnosis. The …

PET radiopharmaceuticals for specific bacteria imaging: a systematic review

S Auletta, M Varani, R Horvat, F Galli, A Signore… - Journal of clinical …, 2019 - mdpi.com
Background: Bacterial infections are still one of the main factors associated with mortality
worldwide. Many radiopharmaceuticals were developed for bacterial imaging, both with …

Presurgery and postsurgery: advancements in artificial intelligence and machine learning models for enhancing patient management in infective endocarditis

RM Odat, MDM Marsool, D Nguyen… - … Journal of Surgery, 2024 - journals.lww.com
Infective endocarditis (IE) is a severe infection of the inner lining of the heart, known as the
endocardium. It is characterized by a range of symptoms and has a complicated pattern of …

[HTML][HTML] Nuclear imaging for immune cell tracking in vivo–Comparison of various cell labeling methods and their application

Ł Kiraga, P Kucharzewska, S Paisey, Ł Cheda… - Coordination chemistry …, 2021 - Elsevier
There is currently great interest in the development of cell-based therapies, particularly
those focused on the idea of exploiting systemically administered immune cells for …

Diagnostic Performance of PET or PET/CT Using 18F-FDG Labeled White Blood Cells in Infectious Diseases: A Systematic Review and a Bivariate Meta-Analysis

M Meyer, N Testart, M Jreige, C Kamani, M Moshebah… - Diagnostics, 2019 - mdpi.com
Background: Diagnostic performance of positron emission tomography using white blood
cells labeled with fluorine-18-fluorodeoxyglucose (18F-FDG-WBC PET or PET/CT) in …

First-in-human infection imaging with 89Zr-labelled leukocytes and comparison of scan quality with [99mTc]Tc-HMPAO-labelled leukocytes

M Kahts, B Summers, AN Ndlela, A Gutta… - Frontiers in Nuclear …, 2024 - frontiersin.org
Introduction Nuclear medicine infection imaging is routinely performed with the use of
leukocytes radiolabelled with technetium-99m hexamethylpropyleneamine oxime ([99mTc] …

FDG PET/CT of infection: should it replace labeled leukocyte scintigraphy of inpatients?

EH Dibble, DC Yoo, GL Baird… - American Journal of …, 2019 - Am Roentgen Ray Soc
OBJECTIVE. The purpose of this study was to compare the sensitivity, specificity, and
helpfulness to referring clinicians of labeled leukocyte scintigraphy versus FDG PET/CT in …

Infection imaging using [18F] FDG-labelled white blood cell positron emission tomography–computed tomography

VS Krishnaraju, H Singh, R Kumar… - The British Journal of …, 2021 - academic.oup.com
Localizing the sites of infection in the body is possible in nuclear medicine using a variety of
radiopharmaceuticals that target different components of the infective and inflammatory …

Imaging of bacteria: is there any hope for the future based on past experience?

T Ebenhan, E Lazzeri… - Current Pharmaceutical …, 2018 - ingentaconnect.com
Infectious diseases remain a major health problem and cause of death worldwide. It is
expected that the socio-economic impact will further intensify due to escalating resistance to …