Exosomal miRNAs as a promising source of biomarkers in colorectal cancer progression

T Bakhsh, S Alhazmi, NA Alburae, A Farsi… - International Journal of …, 2022 - mdpi.com
Colorectal cancer (CRC) is the third most common type of cancer worldwide amongst males
and females. CRC treatment is multidisciplinary, often including surgery, chemotherapy, and …

Portrait of cancer stem cells on colorectal cancer: molecular biomarkers, signaling pathways and miRNAome

A Angius, AM Scanu, C Arru, MR Muroni… - International journal of …, 2021 - mdpi.com
Colorectal cancer (CRC) is a leading cause of cancer death worldwide, and about 20% is
metastatic at diagnosis and untreatable. Increasing evidence suggests that the …

A deep learning model predicts the presence of diverse cancer types using circulating tumor cells

S Albaradei, N Alganmi, A Albaradie, E Alharbi… - Scientific reports, 2023 - nature.com
Circulating tumor cells (CTCs) are cancer cells that detach from the primary tumor and
intravasate into the bloodstream. Thus, non-invasive liquid biopsies are being used to …

Construction of a prognostic signature associated with liver metastases for prognosis and immune response prediction in colorectal cancer

C Liu, Z Lu, J Yan, D Xue, X He, W Huang… - Frontiers in …, 2023 - frontiersin.org
Background As the most common gastrointestinal malignancy worldwide, liver metastases
occur in half colorectal cancer (CRC) patients. Early detection can help treat them early and …

Predictive efficacy of MiR-125b-5p, MiR-17-5p, and MiR-185-5p in liver metastasis and chemotherapy response among advanced stage colorectal cancer patients

D Sur, L Balacescu, SS Cainap, S Visan, L Pop… - Frontiers in …, 2021 - frontiersin.org
MicroRNAs (miRNAs), a class of small non-coding RNAs represent potential biomarkers for
colorectal cancer (CRC). The study hypothesized that miRNAs associated with liver …

Epigenetic and metabolic reprogramming in inflammatory bowel diseases: diagnostic and prognostic biomarkers in colorectal cancer

Z Deris Zayeri, A Parsi, S Shahrabi, M Kargar… - Cancer Cell …, 2023 - Springer
Background and aim" Inflammatory bowel disease"(IBD) is a chronic, relapsing inflammatory
disease of the intestinal tract that typically begins at a young age and might transit to …

[HTML][HTML] miR-328-3p overexpression attenuates the malignant proliferation and invasion of liver cancer via targeting Endoplasmic Reticulum Metallo Protease 1 to …

H Lu, J Hu, J Li, W Lu, X Deng… - Annals of translational …, 2020 - ncbi.nlm.nih.gov
Background Liver cancer is one of the most common cancers worldwide. microRNAs
(miRNAs) have been recognized as minimally invasive prognostic markers for distinct types …

[HTML][HTML] The role of miRNAs during endoplasmic reticulum stress induced apoptosis in digestive cancer

Y Zhang, S Huang, G Yang, L Zou, X Huang… - Journal of …, 2021 - ncbi.nlm.nih.gov
Digestive cancer is one of the leading causes of cancer mortality in the world. Despite a
number of studies being conducted, the exact mechanism for treating digestive cancer has …

MicroRNAs as potential investigative and predictive biomarkers in colorectal cancer

N Yaghoubi, FZ Avval, M Khazaei… - Cellular …, 2021 - Elsevier
Colorectal cancer (CRC) is a noticeable reason of cancer-associated deaths with a high
incidence and mortality rate. Countless effort have been put into the improving clinical …

Multi-omics analysis of the tumor microenvironment in liver metastasis of colorectal cancer identified FJX1 as a novel biomarker

J Zou, H Zhang, Y Huang, W Xu, Y Huang, S Zuo… - Frontiers in …, 2022 - frontiersin.org
Colorectal cancer incidence and mortality have increased in recent years, with more than
half of patients who died of colorectal cancer developing liver metastases. Consequently …