Uncertainty about potential future threats and the associated anxious anticipation represents
a key feature of anxiety. However, the neural systems that underlie the subjective …

A well‐documented amygdala‐dorsomedial prefrontal circuit is theorized to promote
attention to threat (“threat vigilance”). Prior research has implicated a relationship between …

The periaqueductal gray (PAG) is a small midbrain structure that surrounds the cerebral
aqueduct, regulates brain–body communication, and is often studied for its role in “fight-or …

Premenstrual dysphoric disorder (PMDD) is a severe subtype of premenstrual syndrome in
women of reproductive age, with its pathogenesis linked to the heightened sensitivity of type …

Computational models of associative learning posit that negative prediction errors (PEs)
arising from the omission of aversive outcomes weaken aversive Pavlovian associations …

Over the past century, research has helped us build a fundamental understanding of the
neurobiological underpinnings of anxiety. Specifically, anxiety engages a broad range of …

Il peso dei disturbi dell'umore continua a crescere, con circa un terzo dei pazienti che non
risponde agli antidepressivi. Una diagnosi accurata e tempestiva è essenziale per la …

To survive, animals have to finely regulate their threat assessment and escape behavior. In
mice, the brainstem dorsal periaqueductal grey (dPAG) generates innate defensive …

Graph theory provides a promising technique to investigate Alzheimer's disease (AD)-
related alterations in brain connectivity. However, discrepancies exist in the reported …