Physiology and physical chemistry of bile acids

MC Di Gregorio, J Cautela, L Galantini - International journal of molecular …, 2021 - mdpi.com
Bile acids (BAs) are facial amphiphiles synthesized in the body of all vertebrates. They
undergo the enterohepatic circulation: they are produced in the liver, stored in the …

Research progress in strategies to improve the efficacy and safety of doxorubicin for cancer chemotherapy

M Sohail, Z Sun, Y Li, X Gu, H Xu - Expert review of anticancer …, 2021 - Taylor & Francis
Introduction DOX exerts strong anticancer activity and is commonly used to treat different
cancers, including bone sarcomas, soft tissues, bladder, ovary, stomach, thyroid, breast …

Self-assembly of bile salts and their mixed aggregates as building blocks for smart aggregates

PY Parekh, VI Patel, MR Khimani, P Bahadur - Advances in Colloid and …, 2023 - Elsevier
The present communication offers a comprehensive overview of the self-assembly of bile
salts emphasizing their mixed smart aggregates with a variety of amphiphiles. Using an …

Cubosomes stabilized by a polyphosphoester-analog of Pluronic F127 with reduced cytotoxicity

M Fornasier, S Biffi, B Bortot, P Macor, A Manhart… - Journal of colloid and …, 2020 - Elsevier
Lyotropic liquid crystalline nanoparticles with bicontinuous cubic internal nanostructure,
known as cubosomes, have been proposed as nanocarriers in various medical applications …

Design and characterization of glyceryl monooleate-nanostructures containing doxorubicin hydrochloride

A Gagliardi, D Cosco, BP Udongo, L Dini, G Viglietto… - Pharmaceutics, 2020 - mdpi.com
Glyceryl monooleate (GMO) is one of the most popular amphiphilic lipids, which, in the
presence of different amounts of water and a proper amount of stabilizer, can promote the …

A novel multifunctional NCQDs-based injectable self-crosslinking and in situ forming hydrogel as an innovative stimuli responsive smart drug delivery system for …

S Türk, I Altınsoy, GÇ Efe, M Ipek, M Özacar… - Materials Science and …, 2021 - Elsevier
In this work, we offer an easy approach to develop a novel injectable, pH sensitive and in
situ smart drug delivery system for use in cancer treatments. The developed hydrogels …

Tuning lipid structure by bile salts: Hexosomes for topical administration of catechin

M Fornasier, R Pireddu, A Del Giudice, C Sinico… - Colloids and Surfaces B …, 2021 - Elsevier
The delivery of bio-active molecules through the skin is challenging given the complex
structure of its outer layer, the stratum corneum. Here we explore the possibility to …

[HTML][HTML] Determination of the optimal pH for doxorubicin encapsulation in polymeric micelles

L Desiderio, NS Gjerde, E Tasca, L Galantini… - Journal of Colloid and …, 2024 - Elsevier
Hypothesis The anticancer drug doxorubicin hydrochloride (DX) shows a high solubility in
aqueous media thanks to the positive charge in the ammonium group. This feature …

A fluorescence study of the interaction of anticancer drug molecule doxorubicin hydrochloride in pluronic P123 and F127 micelles

SK Behera, ME Mohanty, M Mohapatra - Journal of Fluorescence, 2021 - Springer
Drug delivery systems for the sustained and target delivery of doxorubicin to tumor cells are
a topic of interest due to the efficacy of the doxorubicin in cancer treatment. The use of …

Poloxamer/sodium cholate co-formulation for micellar encapsulation of doxorubicin with high efficiency for intracellular delivery: An in-vitro bioavailability study

E Tasca, P Andreozzi, A Del Giudice, L Galantini… - Journal of Colloid and …, 2020 - Elsevier
Hypothesis Doxorubicin hydrochloride (DX) is widely used as a chemotherapeutic agent,
though its severe side-effects limit its clinical use. A way to overcome these limitations is to …