Irisin: a hope in understanding and managing obesity and metabolic syndrome

LI Arhire, L Mihalache, M Covasa - Frontiers in endocrinology, 2019 - frontiersin.org
White adipose tissue (WAT) is an endocrine organ highly integrated in homeostasis and
capable of establishing ways of communicating and influencing multiple metabolic …

Irisin, an exercise-induced bioactive peptide beneficial for health promotion during aging process

H Zhang, X Wu, J Liang, M Kirberger, N Chen - Ageing research reviews, 2022 - Elsevier
Irisin is an exercise-induced myokine expressed as a bioactive peptide in multiple tissues
and organs, and exercise and cold exposure are the major inducers for its secretion. Irisin …

Metabolic health—the role of adipo-myokines

C Graf, N Ferrari - International journal of molecular sciences, 2019 - mdpi.com
Obesity is now a worldwide epidemic. In recent years, different phenotypes of obesity,
ranging from metabolically healthy normal weight to metabolically unhealthy obese, were …

Role of Irisin in Endocrine and Metabolic Disorders—Possible New Therapeutic Agent?

L Leustean, C Preda, L Teodoriu, L Mihalache… - Applied Sciences, 2021 - mdpi.com
Irisin is a novel hormone that provides a possible solution for the treatment of metabolic
disorders. Discovered in 2012 by Boström et al., irisin very quickly became an interesting …

Fibronectin type III domain-containing 5 in cardiovascular and metabolic diseases: a promising biomarker and therapeutic target

X Zhang, C Hu, H Wu, Z Ma, Q Tang - Acta Pharmacologica Sinica, 2021 - nature.com
Cardiovascular and metabolic diseases are the leading causes of death and disability
worldwide and impose a tremendous socioeconomic burden on individuals as well as the …

Short-and long-term effects of concurrent aerobic and resistance training on circulating irisin levels in overweight or obese individuals: a systematic review and meta …

Y Cheng, J Ma, S Bo - PeerJ, 2024 - peerj.com
Background Concurrent training (CT) is emerging as a practical and effective approach to
enhance body composition, cardiovascular function, and muscle mass, thereby elevating …

The exercise-instrumental music program and irisin levels in younger non-professional athletes

S Sugiharto, D Merawati… - Comparative …, 2022 - wageningenacademic.com
A passive lifestyle and lack of exercise are triggering factors in increasing metabolic
syndrome, whereas metabolic syndrome is associated with increased morbidity and …

Myokine–adipokine cross-talk: potential mechanisms for the association between plasma irisin and adipokines and cardiometabolic risk factors in Mexican children …

AM Gonzalez-Gil, M Peschard-Franco… - Diabetology & metabolic …, 2019 - Springer
Background Adipokines and the myokine irisin, involved in mechanisms associated with
obesity and metabolic syndrome (MS), are understudied in the pediatric population …

Irisin improves adiposity and exercise tolerance in a rat model of postmenopausal obesity through enhancing adipo-myocyte thermogenesis

REAE Gheit, RL Younis, MH El-Saka… - Journal of physiology …, 2022 - Springer
The prevalence of obesity and its associated metabolic disorders, along with their
healthcare costs, is rising exponentially. Irisin, an adipomyokine, may serve as a critical …

Irisin and Cardiometabolic disorders in obesity: a systematic review

JS Pinho-Jr, FA Camacho, CS Cavararo… - International Journal …, 2023 - Wiley Online Library
Background. Overweight and obesity are global health issues, impacting a significant
portion of young adults. Obesity is a complex condition influenced by genetics and …