The dark side of foetal bovine serum in extracellular vesicle studies

O Urzì, R Olofsson Bagge… - Journal of extracellular …, 2022 - Wiley Online Library
Extracellular vesicles (EVs) have been shown to be involved in cell‐cell communication and
to take part in both physiological and pathological processes. Thanks to their exclusive …

Impact of endocrine disruptors upon non-genetic inheritance

D Montjean, AS Neyroud, MG Yefimova… - International Journal of …, 2022 - mdpi.com
Similar to environmental factors, EDCs (endocrine-disrupting chemicals) can influence gene
expression without modifying the DNA sequence. It is commonly accepted that the …

Hatching is modulated by microRNA-378a-3p derived from extracellular vesicles secreted by blastocysts

KC Pavani, T Meese, OB Pascottini… - Proceedings of the …, 2022 - National Acad Sciences
Extracellular vesicles (EVs) and their cargo microRNAs (miRNAs) are important regulators of
embryo development to the blastocyst stage and beyond. Before implantation can take …

Diversity of extracellular vesicles in human follicular fluid: morphological analysis and quantification

AS Neyroud, RM Chiechio, G Moulin… - International Journal of …, 2022 - mdpi.com
The oocyte microenvironment constituted by the follicular fluid (FF) is a key for the optimal
development of female gametes. Its composition reflects the physiological state of the …

CTC, ctDNA, and exosome in thyroid cancers: a review

W Wang, Z Zheng, J Lei - International journal of molecular sciences, 2023 - mdpi.com
Thyroid cancer has become more common in recent years all around the world. Many issues
still need to be urgently addressed in the diagnosis, treatment, and prognosis of thyroid …

Epigenetic modifications at the center of the barker hypothesis and their transgenerational implications

RJ Ryznar, L Phibbs, LJ Van Winkle - International journal of …, 2021 - mdpi.com
Embryo/fetal nutrition and the environment in the reproductive tract influence the subsequent
risk of developing adult diseases and disorders, as formulated in the Barker hypothesis …

Role of alternative splicing in sex determination in vertebrates

I Gómez-Redondo, B Planells, P Navarrete… - Sexual …, 2021 - karger.com
During the process of sex determination, a germ-cell-containing undifferentiated gonad is
converted into either a male or a female reproductive organ. Both the composition of sex …

Maternal metabolic health and fertility: we should not only care about but also for the oocyte!

J Leroy, B Meulders, K Moorkens… - Reproduction …, 2022 - CSIRO Publishing
Metabolic disorders due to obesity and unhealthy lifestyle directly alter the oocyte's
microenvironment and impact oocyte quality. Oxidative stress and mitochondrial dysfunction …

Isolation of extracellular vesicles from human follicular fluid: size-exclusion chromatography versus ultracentrifugation

M Soares, MM Pinto, RJ Nobre, LP de Almeida… - Biomolecules, 2023 - mdpi.com
Follicular fluid (FF) is the microenvironment where a growing oocyte develops. Intrafollicular
communication ensures oocyte competence and is carried out through paracrine signaling …

Cathepsin-L secreted by high-quality bovine embryos exerts an embryotrophic effect in vitro

A Raes, E Wydooghe, KC Pavani… - International Journal of …, 2023 - mdpi.com
While human in vitro embryo production is generally performed individually, animal models
have shown that culturing embryos in groups improves blastocyst yield and quality …