Biological function of antimicrobial peptides on suppressing pathogens and improving host immunity

Z Lyu, P Yang, J Lei, J Zhao - Antibiotics, 2023 - mdpi.com
The emergence of drug-resistant genes and concerns about food safety caused by the
overuse of antibiotics are becoming increasingly prominent. There is an urgent need for …

Role of milk-derived antibacterial peptides in modern food biotechnology: Their synthesis, applications and future perspectives

MU Khan, M Pirzadeh, CY Förster, S Shityakov… - Biomolecules, 2018 - mdpi.com
Milk-derived antibacterial peptides (ABPs) are protein fragments with a positive influence on
the functions and conditions of a living organism. Milk-derived ABPs have several useful …

Assembly of histidine-rich protein materials controlled through divalent cations

H López-Laguna, U Unzueta, O Conchillo-Solé… - Acta biomaterialia, 2019 - Elsevier
Nanostructured protein materials show exciting biomedical applications, since both structure
and function can be genetically programmed. In particular, self-assembling histidine-rich …

Design of Protegrin-1 Analogs with Improved Antibacterial Selectivity

IA Bolosov, PV Panteleev, SV Sychev, VA Khokhlova… - Pharmaceutics, 2023 - mdpi.com
Protegrin-1 (PG-1) is a cationic β-hairpin pore-forming antimicrobial peptide having a
membranolytic mechanism of action. It possesses in vitro a potent antimicrobial activity …

Rediscovery of antimicrobial peptides as therapeutic agents

M Ryu, J Park, JH Yeom, M Joo, K Lee - Journal of Microbiology, 2021 - Springer
In recent years, the occurrence of antibiotic-resistant pathogens is increasing rapidly. There
is growing concern as the development of antibiotics is slower than the increase in the …

Protegrin-1 cytotoxicity towards mammalian cells positively correlates with the magnitude of conformational changes of the unfolded form upon cell interaction

N Soundrarajan, S Park, Q Le Van Chanh, H Cho… - Scientific Reports, 2019 - nature.com
Abstract Porcine protegrin-1 (PG-1) is a broad-spectrum antimicrobial peptide (AMP) with
potent antimicrobial activities. We produced recombinant PG-1 and evaluated its cytotoxicity …

[HTML][HTML] Use of sheep myeloid antimicrobial peptide (SMAP-18) and siderophore Pyochelin for mitigation of aerospace fuel-degrading microbes

ALB Schroeder, O Radwan, ON Ruiz… - International …, 2025 - Elsevier
Sustainment of aviation fuel infrastructure is expensive and requires frequent testing for
hydrocarbon-degrading microbes to assure safeguarding of fuel quality and engineering …

Effective Healing of Staphylococcus aureus-Infected Wounds in Pig Cathelicidin Protegrin-1-Overexpressing Transgenic Mice

N Soundrarajan, P Somasundaram, D Kim… - International Journal of …, 2023 - mdpi.com
Antimicrobial peptides (AMPs) are promising alternatives to existing treatments for multidrug-
resistant bacteria-infected wounds. Therefore, the effect of protegrin-1 (PG1), a potent …

Potential of Bacteriocins from Lactobacillus taiwanensis for Producing Bacterial Ghosts as a Next Generation Vaccine

SW Kim, YJ Ha, KH Bang, S Lee, JH Yeo, HS Yang… - Toxins, 2020 - mdpi.com
Bacteriocins are functionally diverse toxins produced by most microbes and are potent
antimicrobial peptides (AMPs) for bacterial ghosts as next generation vaccines. Here, we …

Carbon nanodot impregnated fluorescent nanofibers for in vivo monitoring and accelerating full-thickness wound healing

P Pal, B Das, P Dadhich, A Achar… - Journal of Materials …, 2017 - pubs.rsc.org
Semiconductor quantum dots are overwhelmingly used for in situ monitoring and imaging of
cell–scaffold interactions. However, quantum dots suffer from oxidative biodegradation in …