Fatty acids (FAs) are stored safely in the form of triacylglycerol (TAG) in lipid droplet (LD)
organelles by professional storage cells called adipocytes. These lipids are mobilized …

Lipolysis of white adipose tissue triacylglycerol stores results in the liberation of glycerol and
nonesterified fatty acids that are released into the vasculature for use by other organs as …

Lipid droplets form the main lipid store in eukaryotic cells. Although all cells seem to be able
to generate lipid droplets, their biogenesis, regulatory mechanisms and interactions with …

This work investigated how cold stress induces the appearance of brown adipocytes (BAs)
in brown and white adipose tissues (WATs) of adult mice. In interscapular brown adipose …

The PAT family of lipid droplet proteins includes 5 members in mammals: perilipin, adipose
differentiation-related protein (ADRP), tail-interacting protein of 47 kDa (TIP47), S3–12, and …

Fatty acids (FAs) are essential components of all lipid classes and pivotal substrates for
energy production in all vertebrates. Additionally, they act directly or indirectly as signaling …

Autophagy is a conserved quality-control pathway that degrades cytoplasmic contents in
lysosomes. Autophagy degrades lipid droplets through a process termed lipophagy …

The mobilization of stored lipid by hormones is a fundamental function of fat cells, and there
is strong evidence that perilipin (Plin), a lipid droplet scaffold, and adipose tissue triglyceride …

This study investigated the molecular mechanisms by which a high-fat diet (HFD)
dysregulates lipolysis and lipid metabolism in mouse epididymal (visceral, VC) and inguinal …

The term lipophagy is used to describe the autophagic degradation of lipid droplets, the
main lipid storage organelles of eukaryotic cells. Ever since its discovery in 2009, lipophagy …