Efferocytosis in health and disease
The clearance of apoptotic cells by professional and non-professional phagocytes—a
process termed 'efferocytosis'—is essential for the maintenance of tissue homeostasis …
process termed 'efferocytosis'—is essential for the maintenance of tissue homeostasis …
Efferocytosis and its role in inflammatory disorders
Y Ge, M Huang, Y Yao - Frontiers in cell and developmental biology, 2022 - frontiersin.org
Efferocytosis is the effective clearance of apoptotic cells by professional and non-
professional phagocytes. The process is mechanically different from other forms of …
professional phagocytes. The process is mechanically different from other forms of …
[HTML][HTML] M. tuberculosis-induced necrosis of infected neutrophils promotes bacterial growth following phagocytosis by macrophages
Neutrophils represent the main infected cell population in the lungs of active tuberculosis
patients. Efficient removal of infected and dying neutrophils is required to protect the …
patients. Efficient removal of infected and dying neutrophils is required to protect the …
Macrophages in age-related chronic inflammatory diseases
Chronic inflammation is the common pathological basis for such age-associated diseases
as cardiovascular disease, diabetes, cancer and Alzheimer's disease. A multitude of bodily …
as cardiovascular disease, diabetes, cancer and Alzheimer's disease. A multitude of bodily …
The role of efferocytosis‐fueled macrophage metabolism in the resolution of inflammation
The phagocytosis of dying cells by macrophages, termed efferocytosis, is a tightly regulated
process that involves the sensing, binding, engulfment, and digestion of apoptotic cells …
process that involves the sensing, binding, engulfment, and digestion of apoptotic cells …
Anti-inflammatory mechanisms triggered by apoptotic cells during their clearance
In the human body, billions of cells die by apoptosis every day. The subsequent clearance of
apoptotic cells by phagocytosis is normally efficient enough to prevent secondary necrosis …
apoptotic cells by phagocytosis is normally efficient enough to prevent secondary necrosis …
Oxidative stress as a key modulator of cell fate decision in osteoarthritis and osteoporosis: a narrative review
J Riegger, A Schoppa, L Ruths… - Cellular & molecular …, 2023 - Springer
During aging and after traumatic injuries, cartilage and bone cells are exposed to various
pathophysiologic mediators, including reactive oxygen species (ROS), damage-associated …
pathophysiologic mediators, including reactive oxygen species (ROS), damage-associated …
Types of necroinflammation, the effect of cell death modalities on sterile inflammation
Distinct types of immune responses are activated by infections, which cause the
development of type I, II, or III inflammation, regulated by Th1, Th2, Th17 helper T cells and …
development of type I, II, or III inflammation, regulated by Th1, Th2, Th17 helper T cells and …
Macrophage efferocytosis in health and disease
S Razi, J Yaghmoorian Khojini… - Cell biochemistry …, 2023 - Wiley Online Library
Creating cellular homeostasis within a defined tissue typically relates to the processes of
apoptosis and efferocytosis. A great example here is cell debris that must be removed to …
apoptosis and efferocytosis. A great example here is cell debris that must be removed to …
Myeloid-epithelial-reproductive receptor tyrosine kinase and milk fat globule epidermal growth factor 8 coordinately improve remodeling after myocardial infarction via …
KY Howangyin, I Zlatanova, C Pinto, A Ngkelo… - Circulation, 2016 - Am Heart Assoc
Background—In infarcted heart, improper clearance of dying cells by activated neighboring
phagocytes may precipitate the transition to heart failure. We analyzed the coordinated role …
phagocytes may precipitate the transition to heart failure. We analyzed the coordinated role …