Hepatocellular carcinoma: new developments

P Ganesan, LM Kulik - Clinics in liver disease, 2023 - liver.theclinics.com
Hepatocellular carcinoma (HCC) is the fourth leading cause of cancer-related mortality
worldwide and a leading cause of death in cirrhosis. The prognosis in HCC is poor, with …

Biomarkers in hepatocellular carcinoma: diagnosis, prognosis and treatment response assessment

F Piñero, M Dirchwolf, MG Pessôa - Cells, 2020 - mdpi.com
Hepatocellular carcinoma (HCC) is one of the main cancer-related causes of death
worldwide. Thus, there is a constant search for improvement in screening, diagnosis, and …

The functional and clinical roles of liquid biopsy in patient-derived models

Z Zhu, E Hu, H Shen, J Tan, S Zeng - Journal of Hematology & Oncology, 2023 - Springer
The liquid biopsy includes the detection of circulating tumor cells (CTCs) and CTC clusters
in blood, as well as the detection of, cell-free DNA (cfDNA)/circulating tumor DNA (ctDNA) …

[HTML][HTML] Efficacy and safety of camrelizumab plus apatinib during the perioperative period in resectable hepatocellular carcinoma: a single-arm, open label, phase II …

Y Xia, W Tang, X Qian, X Li, F Cheng… - … for Immunotherapy of …, 2022 - ncbi.nlm.nih.gov
Objective This study aimed to assess the efficacy and safety of camrelizumab plus apatinib
in patients with resectable hepatocellular carcinoma (HCC) as neoadjuvant therapy …

[HTML][HTML] Circulating tumor cells in hepatocellular carcinoma: single-cell based analysis, preclinical models, and clinical applications

Q Zhang, Y Rong, K Yi, L Huang, M Chen, F Wang - Theranostics, 2020 - ncbi.nlm.nih.gov
Circulating tumor cells (CTCs) are shed into the bloodstream from primary tumors and
metastatic lesions and provide significant information about tumor progression and …

Clinical implication of circulating tumor cells expressing epithelial mesenchymal transition (EMT) and cancer stem cell (CSC) markers and their perspective in HCC: a …

S Orrapin, S Udomruk, W Lapisatepun, S Moonmuang… - Cancers, 2022 - mdpi.com
Simple Summary One of the major problems regarding hepatocellular carcinoma (HCC) is
the development of metastasis and recurrence, even in patients with an early stage …

Advancements in the diagnosis of hepatocellular carcinoma

NS Parra, HM Ross, A Khan, M Wu, R Goldberg… - International Journal of …, 2023 - mdpi.com
Hepatocellular carcinoma (HCC) is the most common primary liver malignancy, with
increasing global incidence. Morbidity and mortality associated with HCC remains high, and …

Circulating tumor cells in the early detection of human cancers

Z Feng, Y Feng, N Wang - Handbook of Cancer and Immunology, 2022 - Springer
Cancer is considered as the leading cause of death and the major barrier of longevity
globally. The high mortality of cancer is due to the malignant spread. However, if the disease …

Urine DNA biomarkers for hepatocellular carcinoma screening

AK Kim, JP Hamilton, SY Lin, TT Chang… - British journal of …, 2022 - nature.com
Background Hepatocellular carcinoma (HCC) occurs in a well-defined high-risk patient
population, but better screening tests are needed to improve sensitivity and efficacy …

HCC biomarkers–state of the old and outlook to future promising biomarkers and their potential in everyday clinical practice

S Schlosser, D Tümen, B Volz, K Neumeyer… - Frontiers in …, 2022 - frontiersin.org
Hepatocellular carcinoma (HCC) is one of the most common and deadly tumors worldwide.
Management of HCC depends on reliable biomarkers for screening, diagnosis, and …