Redox regulation of the actin cytoskeleton and its role in the vascular system

Q Xu, LP Huff, M Fujii, KK Griendling - Free Radical Biology and Medicine, 2017 - Elsevier
The actin cytoskeleton is critical for form and function of vascular cells, serving mechanical,
organizational and signaling roles. Because many cytoskeletal proteins are sensitive to …

Estrogens regulate life and death in mitochondria

CM Klinge - Journal of bioenergetics and biomembranes, 2017 - Springer
Estrogens coordinate and integrate cellular metabolism and mitochondrial activities by direct
and indirect mechanisms mediated by differential expression and localization of estrogen …

Estrogen receptors and estrogen-induced uterine vasodilation in pregnancy

J Bai, QR Qi, Y Li, R Day, J Makhoul… - International journal of …, 2020 - mdpi.com
Normal pregnancy is associated with dramatic increases in uterine blood flow to facilitate the
bidirectional maternal–fetal exchanges of respiratory gases and to provide sole nutrient …

Mapping pregnancy-dependent Sulfhydrome unfolds diverse functions of protein Sulfhydration in human uterine artery

J Bai, F Jiao, AG Salmeron, S Xu, M Xian… - …, 2023 - academic.oup.com
Uterine artery (UA) hydrogen sulfide (H2S) production is augmented in pregnancy and, on
stimulation by systemic/local vasodilators, contributes to pregnancy-dependent uterine …

Quercetin has antimetastatic effects on gastric cancer cells via the interruption of uPA/uPAR function by modulating NF-κb, PKC-δ, ERK1/2, and AMPKα

H Li, C Chen - Integrative cancer therapies, 2018 - journals.sagepub.com
Gastric cancer (GC) is a malignancy with few effective treatment options after metastasis
occurs. Quercetin (Qu) intake has been associated with reduced incidence and slow …

Pregnancy Augments VEGF-Stimulated In Vitro Angiogenesis and Vasodilator (NO and H2S) Production in Human Uterine Artery Endothelial Cells

H Zhang, JC Chen, L Sheibani… - The Journal of …, 2017 - academic.oup.com
Context: Augmented uterine artery (UA) production of vasodilators, including nitric oxide
(NO) and hydrogen sulfide (H2S), has been implicated in pregnancy-associated and agonist …

Gasotransmitters in pregnancy: from conception to uterine involution

DD Guerra, KJ Hurt - Biology of Reproduction, 2019 - academic.oup.com
Gasotransmitters are endogenous small gaseous messengers exemplified by nitric ox ide
(NO), carbon monoxide (CO), and hydrogen sulfide (H2S or sulfide). Gasotransmitters are …

Microglial activation induces nitric oxide signalling and alters protein S‐nitrosylation patterns in extracellular vesicles

N Vassileff, JG Spiers, SE Bamford… - Journal of …, 2024 - Wiley Online Library
Neuroinflammation is an underlying feature of neurodegenerative conditions, often
appearing early in the aetiology of a disease. Microglial activation, a prominent initiator of …

Phosphorylation of cofilin-1 by ERK confers HDAC inhibitor resistance in hepatocellular carcinoma cells via decreased ROS-mediated mitochondria injury

PH Liao, HH Hsu, TS Chen, MC Chen, CH Day, CC Tu… - Oncogene, 2017 - nature.com
Hepatocellular carcinoma (HCC) is the most common type of liver cancer. Despite the
availability of several treatment strategies, resistance to chemotherapeutic agents, which …

Redox regulation, protein S-nitrosylation, and synapse loss in Alzheimer's and related dementias

C Oh, T Nakamura, X Zhang, SA Lipton - Neuron, 2024 - cell.com
Redox-mediated posttranslational modification, as exemplified by protein S-nitrosylation,
modulates protein activity and function in both health and disease. Here, we review recent …