Global treatment of drug addiction costs society billions of dollars annually, but current
psychopharmacological therapies have not been successful at desired rates. The increasing …

Dopamine plays a key role in reward behavior, yet the association of drug dependence as a
chronic, relapsing disorder with the genes encoding the various dopaminergic receptor …

Traditional behavioral genetic studies (eg, twin, adoption studies) have shown that human
personality has moderate to high heritability, but recent molecular behavioral genetic studies …

The heritability of human personality traits is by now well established. However, since the
first reports on associations between specific genetic variants and personality traits, only …

Addiction to opiates and illicit use of psychostimulants is a chronic, relapsing brain disease
that, if left untreated, can cause major medical, social, and economic problems. This article …

This review provides a short overview of the most significant biologically oriented theories of
human personality. Personality concepts of Eysenck, Gray and McNaughton, Cloninger and …

Suicide is one of the leading causes of death among young adults. Both genetic and
personality factors plausibly have a role on suicidal behavior. We focused on the catechol-O …

Dopamine hypotheses of several psychiatric disorders are based upon the clinical benefits
of drugs affecting dopamine transporter or receptors, and have prompted intensive …

Background: Pharmacogenetics uses genetic variation to predict individual differences in
response to medications and holds much promise to improve treatment of addictive …

Efforts to understand the biological processes that increase susceptibility to
methamphetamine (METH) use disorders (ie, abuse, dependence, and psychosis) have …