Gliomas are the common type of brain tumors originating from glial cells. Epidemiologically,
gliomas occur among all ages, more often seen in adults, which males are more susceptible …

Inhibitory immune checkpoint (ICP) molecules are pivotal in inhibiting innate and acquired
antitumor immune responses, a mechanism frequently exploited by cancer cells to evade …

Immune checkpoint (IC) therapy has led to a breakthrough in cancer treatment. However, the
interaction of ICs is controversial in glioma. We detected features of ICs using transcriptome …

Ferroptosis, a newly discovered form of regulated cell death, has been reported to be
associated with multiple cancers, including colorectal cancer (CRC). However, the …

Neuroblastoma (NB) is a highly aggressive pediatric cancer that originates from immature
nerve cells, presenting significant treatment challenges due to therapy resistance. Despite …

In 2021, Suwala et al. described Primary Mismatch Repair Deficient IDH‐mutant
Astrocytoma (PMMRDIA) as a distinct group of gliomas. In unsupervised clustering …

Object: Amplification of the epidermal growth factor receptor (EGFR) and its active mutant
type III (EGFRvIII), frequently occurr in glioblastoma (GBM), contributing to chemotherapy …

Gliomas are the highest prevalent primary central nervous system (CNS) cancers with poor
overall survival rate. There is an urgent need to conduct more research into molecular …

Background The molecular profiling of glioblastoma (GBM) based on transcriptomic analysis
could provide precise treatment and prognosis. However, current subtyping (classic …

Abstract B7-H3 (CD276) is a member of the B7 superfamily and shares up to 30% amino
acid identity with other B7 family members. It is expressed in a wide range of cell types and …