Heart transplantation following donation after circulatory death: expanding the donor pool

SE Scheuer, PC Jansz, PS Macdonald - The Journal of Heart and Lung …, 2021 - Elsevier
Heart transplantation from donation after circulatory death (DCD) donors is a rapidly
expanding practice. In this review, we describe the history and challenges of DCD heart …

Transplantation of hearts donated after circulatory death

CW White, SJ Messer, SR Large, J Conway… - Frontiers in …, 2018 - frontiersin.org
Cardiac transplantation has become limited by a critical shortage of suitable organs from
brain-dead donors. Reports describing the successful clinical transplantation of hearts …

[HTML][HTML] A 5-year single-center early experience of heart transplantation from donation after circulatory-determined death donors

S Messer, S Cernic, A Page, M Berman, P Kaul… - The Journal of Heart and …, 2020 - Elsevier
BACKGROUND In an effort to address the increasing demand for heart transplantation
within the United Kingdom (UK), we established a clinical program of heart transplantation …

Inflammation and oxidative stress in the context of extracorporeal cardiac and pulmonary support

S Hatami, J Hefler, DH Freed - Frontiers in immunology, 2022 - frontiersin.org
Extracorporeal circulation (ECC) systems, including cardiopulmonary bypass, and
extracorporeal membrane oxygenation have been an irreplaceable part of the …

Mitochondrial transplantation for myocardial protection in ex-situ‒perfused hearts donated after circulatory death

A Guariento, IP Doulamis, T Duignan, T Kido… - The Journal of Heart and …, 2020 - Elsevier
BACKGROUND Donation after circulatory death (DCD) offers an additional source of
cardiac allografts, potentially allowing expansion of the donor pool, but is limited owing to …

Donation after circulatory death in heart transplantation: history, outcomes, clinical challenges, and opportunities to expand the donor pool

LK Truby, S Casalinova, CB Patel, R Agarwal… - Journal of Cardiac …, 2022 - Elsevier
Heart transplantation remains the gold-standard therapy for end-stage heart failure; the
expected median survival range is 12–13 years. More than 30,000 heart transplants have …

Mimicking “J-shaped” and anisotropic stress–strain behavior of human and porcine aorta by fabric-reinforced elastomer composites

D Zhalmuratova, TG La, KTT Yu… - … applied materials & …, 2019 - ACS Publications
An ex vivo heart perfusion device preserves the donor heart in a warm beating state during
transfer between extraction and implantation surgeries. One of the current challenges …

Heart transplantation with donation after circulatory death: what have we learned from preclinical studies?

P Niederberger, E Farine, M Raillard… - Circulation: Heart …, 2019 - Am Heart Assoc
Heart transplantation remains the preferred option for improving quality of life and survival
for patients suffering from end-stage heart failure. Unfortunately, insufficient supply of …

Ex situ heart perfusion: the past, the present, and the future

L Wang, GA MacGowan, S Ali, JH Dark - The Journal of Heart and Lung …, 2021 - Elsevier
Despite the advancements in medical treatment, mechanical support, and stem cell therapy,
heart transplantation remains the most effective treatment for selected patients with …

Cardiac graft assessment in the era of machine perfusion: current and future biomarkers

M Bona, RK Wyss, M Arnold… - Journal of the …, 2021 - Am Heart Assoc
Heart transplantation remains the treatment of reference for patients experiencing end‐stage
heart failure; unfortunately, graft availability through conventional donation after brain death …