From basics to clinical: a comprehensive review on spinal cord injury

NA Silva, N Sousa, RL Reis, AJ Salgado - Progress in neurobiology, 2014 - Elsevier
Spinal cord injury (SCI) is a devastating neurological disorder that affects thousands of
individuals each year. Over the past decades an enormous progress has been made in our …

Feeding behaviour of broiler chickens: a review on the biomechanical characteristics

DP Neves, TM Banhazi, IA Nääs - Brazilian Journal of Poultry Science, 2014 - SciELO Brasil
Feed related costs are the main drivers of profitability of commercial poultry farms, and good
nutrition is mainly responsible for the exceptional growth rate responses of current poultry …

Astrocytic CX43 hemichannels and gap junctions play a crucial role in development of chronic neuropathic pain following spinal cord injury

MJ Chen, B Kress, X Han, K Moll, W Peng, RR Ji… - Glia, 2012 - Wiley Online Library
Chronic neuropathic pain is a frequent consequence of spinal cord injury (SCI). Yet despite
recent advances, upstream releasing mechanisms and effective therapeutic options remain …

Bace1 and Neuregulin‐1 cooperate to control formation and maintenance of muscle spindles

C Cheret, M Willem, FR Fricker, H Wende… - The EMBO …, 2013 - embopress.org
The protease β‐secretase 1 (Bace1) was identified through its critical role in production of
amyloid‐β peptides (Aβ), the major component of amyloid plaques in Alzheimer's disease …

Following spinal cord injury, PDE4B drives an acute, local inflammatory response and a chronic, systemic response exacerbated by gut dysbiosis and endotoxemia

SA Myers, L Gobejishvili, SS Ohri, CG Wilson… - Neurobiology of …, 2019 - Elsevier
Emerging evidence links changes in the gut microbiome and intestinal barrier function to
alterations in CNS function. We examined the role of endotoxin-responsive, cAMP-specific …

Genetic disruption of WASHC4 drives endo-lysosomal dysfunction and cognitive-movement impairments in mice and humans

JL Courtland, TWA Bradshaw, G Waitt, EJ Soderblom… - Elife, 2021 - elifesciences.org
Mutation of the Wiskott–Aldrich syndrome protein and SCAR homology (WASH) complex
subunit, SWIP, is implicated in human intellectual disability, but the cellular etiology of this …

[HTML][HTML] Grafted human ESC-derived astroglia repair spinal cord injury via activation of host anti-inflammatory microglia in the lesion area

J Wang, P Jiang, W Deng, Y Sun, Y Liu - Theranostics, 2022 - ncbi.nlm.nih.gov
Grafted astroglia/astrocytes exhibit neuroprotective effects and improve functional recovery
after injury to the central nervous system. This study sought to elucidate their ability to repair …

Remodeling of lumbar motor circuitry remote to a thoracic spinal cord injury promotes locomotor recovery

Y Wang, W Wu, X Wu, Y Sun, YP Zhang, LX Deng… - Elife, 2018 - elifesciences.org
Retrogradely-transported neurotrophin signaling plays an important role in regulating neural
circuit specificity. Here we investigated whether targeted delivery of neurotrophin-3 (NT-3) to …

Age exacerbates microglial activation, oxidative stress, inflammatory and NOX2 gene expression, and delays functional recovery in a middle-aged rodent model of …

RE von Leden, G Khayrullina, KE Moritz… - Journal of …, 2017 - Springer
Background Spinal cord injury (SCI) among people over age 40 has been steadily
increasing since the 1980s and is associated with worsened outcome than injuries in young …

The need for speed in rodent locomotion analyses

RJ Batka, TJ Brown, KP Mcmillan… - The Anatomical …, 2014 - Wiley Online Library
Locomotion analysis is now widely used across many animal species to understand the
motor defects in disease, functional recovery following neural injury, and the effectiveness of …