INPP5E and coordination of signaling networks in cilia

R Zhang, J Tang, T Li, J Zhou, W Pan - Frontiers in Molecular …, 2022 - frontiersin.org
Primary cilia are ubiquitous mechanosensory organelles that specifically coordinate a series
of cellular signal transduction pathways to control cellular physiological processes during …

The impact of membrane protein diffusion on GPCR signaling

HH Boltz, A Sirbu, N Stelzer, P de Lanerolle… - Cells, 2022 - mdpi.com
Spatiotemporal signal shaping in G protein-coupled receptor (GPCR) signaling is now a well-
established and accepted notion to explain how signaling specificity can be achieved by a …

Potential of Single‐Molecule Live‐Cell Imaging for Chemical Translational Biology

H Yoshimura - Chembiochem, 2021 - Wiley Online Library
Single‐molecule live‐cell imaging is the most direct approach for monitoring the motility of
molecules in living cells. Considering the relationship between the motility of molecules and …

Triple-color single-molecule imaging for analysis of the role of receptor oligomers in signal transduction

H Yoshimura - Biophysics and Physicobiology, 2022 - jstage.jst.go.jp
Membrane receptors provide interfaces of various extracellular stimuli to transduce the
signal into the cell. Receptors are required to possess such conflicting properties as high …

細胞膜受容体の集合とシグナル伝達の3 色同時蛍光1 分子イメージングによる解析

吉村英哲 - 生物物理, 2021 - jstage.jst.go.jp
なかった理由として, 全ての FPR1 にリガンドが結合しておらずリガンドが結合した FPR1
と結合していない FPR1 が混在していることが可能性として挙げられる. 2 色同時 1 分子観察では …