Pyridine: the scaffolds with significant clinical diversity
The nitrogen-bearing heterocycle pyridine in its several analogous forms occupies an
important position as a precious source of clinically useful agents in the field of medicinal …
important position as a precious source of clinically useful agents in the field of medicinal …
The biology and chemistry of antifungal agents: a review
MK Kathiravan, AB Salake, AS Chothe… - Bioorganic & medicinal …, 2012 - Elsevier
In recent years their has been an increased use of antifungal agents and has resulted in the
development of resistance to drugs. Currently, use of standard antifungal therapies can be …
development of resistance to drugs. Currently, use of standard antifungal therapies can be …
Synthesis of novel analogs of 2-pyrazoline obtained from [(7-chloroquinolin-4-yl) amino] chalcones and hydrazine as potential antitumor and antimalarial agents
A new series of N-acetyl and N-formyl-pyrazoline derivatives 6 and 7–8 were synthesized by
cyclocondensation reaction of [(7-chloroquinolin-4-yl) amino] chalcones with hydrazine …
cyclocondensation reaction of [(7-chloroquinolin-4-yl) amino] chalcones with hydrazine …
Synthesis and antibacterial activity of some heterocyclic chalcone analogues alone and in combination with antibiotics
TD Tran, TTN Nguyen, TH Do, TNP Huynh, CD Tran… - Molecules, 2012 - mdpi.com
A series of simple heterocyclic chalcone analogues have been synthesized by Claisen
Schmidt condensation reactions between substituted benzaldehydes and heteroaryl methyl …
Schmidt condensation reactions between substituted benzaldehydes and heteroaryl methyl …
Design and synthesis of new N-thioacylated ciprofloxacin derivatives as urease inhibitors with potential antibacterial activity
A new series of N-thioacylated ciprofloxacin 3a–n were designed and synthesized based on
Willgerodt–Kindler reaction. The results of in vitro urease inhibitory assay indicated that …
Willgerodt–Kindler reaction. The results of in vitro urease inhibitory assay indicated that …
Tautomeric origin of dual effects of N1-nicotinoyl-3-(4′-hydroxy-3′-methyl phenyl)-5-[(sub)phenyl]-2-pyrazolines on bacterial and viral strains: POM analyses as …
TB Hadda, MA Ali, V Masand, S Gharby… - Medicinal Chemistry …, 2013 - Springer
In this study, we have amalgamated computational methodologies, viz. Petra, Osiris and
Molinspiration (POM) to identify pharmacophores and antipharmacophores for …
Molinspiration (POM) to identify pharmacophores and antipharmacophores for …
Sulfated polyborate catalyzed Kindler reaction: a rapid, efficient, and green protocol
CK Khatri, AS Mali, GU Chaturbhuj - Monatshefte für Chemie-Chemical …, 2017 - Springer
A rapid, green, and efficient one-pot, three-component Kindler reaction was developed
using a sulfated polyborate catalyst. The method described the reaction of aldehydes …
using a sulfated polyborate catalyst. The method described the reaction of aldehydes …
2-Pyrazolines as biologically active and fluorescent agents, an overview
Nitrogen-containing five-membered heterocyclics play a vital role in pharmaceuticals as well
as medicinal chemistry. Pyrazolines play a significant role among other heterocycles …
as medicinal chemistry. Pyrazolines play a significant role among other heterocycles …
Discovery of anticancer agents from 2-pyrazoline-based compounds
QS Li, BN Shen, Z Zhang, S Luo… - Current medicinal …, 2021 - ingentaconnect.com
As nitrogen-containing five-membered heterocyclic structural units, the substituted pyrazole
derivatives have a broad spectrum of pharmacological activities, especially 4, 5-dihydro-1H …
derivatives have a broad spectrum of pharmacological activities, especially 4, 5-dihydro-1H …
Progress in intermolecular and intramolecular reactions of thioamides with diazo compounds and azides
Reactions of thioamides with nitrogen-rich 1, 3-dipoles, diazo compounds and azides, have
been known for long time already. However in recent years introduction of catalysts of …
been known for long time already. However in recent years introduction of catalysts of …