Abstract The TFOS DEWS II Pathophysiology Subcommittee reviewed the mechanisms
involved in the initiation and perpetuation of dry eye disease. Its central mechanism is …

Tears have a vital function to protect and lubricate the ocular surface. Tear production,
distribution and clearance is tightly regulated by the lacrimal functional unit (LFU) to meet …

Background Dry eye disease (DED) is common; its prevalence around the world varies from
5% to 34%. Its putative pathogenetic mechanisms include hyperosmolarity of the tear film …

Publication of the DEWS report in 2007 established the state of the science of dry eye
disease (DED). Since that time, new evidence suggests that a rethinking of traditional …

Dry eye has been believed to be a chronic, symptomatic ocular surface disease that affects
vision in a limited manner, because it is difficult to detect visual or optical changes using …

Dry eye disease (DED) results in tear film instability and hyperosmolarity, inflammation of the
ocular surface and, ultimately, visual disturbance that can significantly impact a patient's …

We systematically reviewed published research on dry eye disease and its association with
higher order aberrations (HOAs). The purpose of this review was to first determine if an …

Traditional diagnostic tests for dry eye disease (DED), such as fluorescein tear film break‐up
time and the Schirmer test, are often associated with poor reproducibility and reliability …

Purpose.: To evaluate ocular forward light scattering and corneal backward light scattering
in patients with dry eye. Methods.: Thirty-five eyes in 35 patients with dry eye and 20 eyes of …

Purpose To study the perception of light distortion after refractive lens exchange (RLE) with
diffractive multifocal intraocular lenses (IOLs). Setting Clínica Oftalmológica das Antas …