Interactions between the immune system and the nervous system have been described
mostly in the context of diseases. More recent studies have begun to reveal how certain …

Introduction Under specific conditions, a weak lead stimulus, or “prepulse”, can inhibit the
startling effects of a subsequent intense abrupt stimulus. This startle-inhibiting effect of the …

Schizophrenia and autism are thought to result from the interaction between a susceptibility
genotype and environmental risk factors. The offspring of women who experience infection …

Activation of the maternal immune system in rodent models sets in motion a cascade of
molecular pathways that ultimately result in autism-and schizophrenia-related behaviors in …

The objective of this review is to identify a target or biomarker of altered neurochemical
sensitivity that is common to the many animal models of human psychoses associated with …

Categorization of psychotic illnesses into schizophrenic and affective psychoses remains an
ongoing controversy. Although Kraepelinian subtyping of psychosis was historically …

Infection during pregnancy (ie, prenatal infection) increases the risk of psychiatric illnesses
such as schizophrenia and autism in the adult offspring. The present experiments examined …

Abstracts Prepulse inhibition (PPI) of startle is an operational measure of sensorimotor
gating that is often impaired in patients with schizophrenia. Despite the large number of …

We investigated whether prepulse inhibition of the startle response is reduced in siblings of
schizophrenia patients compared to age‐and sex‐matched healthy controls. Nineteen …

Patients with schizophrenia exhibit reduced levels of both prepulse inhibition of the startle
reflex (PPI) and condition-test suppression of the P50 event-related potential. This study …