Breast cancer, the most common type of cancer affecting women, encompasses a collection
of histologic (mainly ductal and lobular) and molecular subtypes exhibiting diverse clinical …

Pro-inflammatory stress is inherent in any cells that are subject to damage or threat of
damage. It is defined by a number of universal components, including oxidative stress …

Although historically, the traditional bidimensional in vitro cell system has been widely used
in research, providing much fundamental information regarding cellular functions and …

The cancer secretome reflects the assortment of proteins released by cancer cells.
Investigating cell secretomes not only provides a deeper knowledge of the healthy and …

Breast cancer has a high occurrence rate globally and its treatment has demonstrated
clinical efficacy with the use of systemic chemotherapy and immune checkpoint blockade …

Cancer-associated fibroblasts (CAFs) play a substantial role in the tumor microenvironment,
exhibiting a strong association with the advancement of various types of cancer, including …

Tumor immunosuppression are prominent characteristics of brain glioma. Current standard
modality including surgical resection and chemoradiotherapy do not significantly improve …

The tumor microenvironment (TME) is composed of a heterogenous population of cells that
exist alongside the extracellular matrix and soluble components. These components can …

Background Lower-grade glioma (LGG) is a primary intracranial tumor that carry a high risk
of malignant transformation and limited therapeutic options. Emerging evidence indicates …

Cancer-associated fibroblasts (CAFs) are highly heterogeneous players that shape the
tumor microenvironment and influence tumor progression, metastasis formation, and …