Artificial intelligence and machine learning approaches using gene expression and variant data for personalized medicine

S Vadapalli, H Abdelhalim, S Zeeshan… - Briefings in …, 2022 - academic.oup.com
Precision medicine uses genetic, environmental and lifestyle factors to more accurately
diagnose and treat disease in specific groups of patients, and it is considered one of the …

Artificial intelligence, healthcare, clinical genomics, and pharmacogenomics approaches in precision medicine

H Abdelhalim, A Berber, M Lodi, R Jain, A Nair… - Frontiers in …, 2022 - frontiersin.org
Precision medicine has greatly aided in improving health outcomes using earlier diagnosis
and better prognosis for chronic diseases. It makes use of clinical data associated with the …

Discovering biomarkers associated and predicting cardiovascular disease with high accuracy using a novel nexus of machine learning techniques for precision …

W DeGroat, H Abdelhalim, K Patel, D Mendhe… - Scientific reports, 2024 - nature.com
Personalized interventions are deemed vital given the intricate characteristics,
advancement, inherent genetic composition, and diversity of cardiovascular diseases …

Genomic approaches to identify and investigate genes associated with atrial fibrillation and heart failure susceptibility

KK Patel, C Venkatesan, H Abdelhalim, S Zeeshan… - Human genomics, 2023 - Springer
Atrial fibrillation (AF) and heart failure (HF) contribute to about 45% of all cardiovascular
disease (CVD) deaths in the USA and around the globe. Due to the complex nature …

Precision medicine with multi-omics strategies, deep phenotyping, and predictive analysis

Z Ahmed - Progress in molecular biology and translational …, 2022 - Elsevier
Precision medicine is driven by the paradigm shift of empowering clinicians to predict the
most appropriate course of action for patients with complex diseases and to improve routine …

Multi-omics strategies for personalized and predictive medicine: past, current, and future translational opportunities

Z Ahmed - Emerging topics in life sciences, 2022 - portlandpress.com
Precision medicine is driven by the paradigm shift of empowering clinicians to predict the
most appropriate course of action for patients with complex diseases and improve routine …

JWES: a new pipeline for whole genome/exome sequence data processing, management, and gene‐variant discovery, annotation, prediction, and genotyping

Z Ahmed, EG Renart, D Mishra, S Zeeshan - FEBS Open bio, 2021 - Wiley Online Library
Whole genome and exome sequencing (WGS/WES) are the most popular next‐generation
sequencing (NGS) methodologies and are at present often used to detect rare and common …

Intelligent health system for the investigation of consenting COVID-19 patients and precision medicine

Z Ahmed - Personalized medicine, 2021 - Taylor & Francis
Advancing frontiers of clinical research, we discuss the need for intelligent health systems to
support a deeper investigation of COVID-19. We hypothesize that the convergence of the …

[HTML][HTML] Comparative genome analysis of Streptococcus strains to identify virulent genes causing neonatal meningitis

J Arya, D Sharma, D Kumar, R Jakhar, A Khichi… - Infection, Genetics and …, 2023 - Elsevier
Abstract Aim To determine Streptococcus agalactiae genes responsible for causing
neonatal meningitis. Background Streptococcus agalactiae strain 2603 V/R is causative …

Investigating genes associated with cardiovascular disease among heart failure patients for translational research and precision medicine

Z Ahmed, S Zeeshan, N Persaud… - Clinical and …, 2023 - Wiley Online Library
Background Cardiovascular disease (CVD) is a leading cause of premature mortality in the
United States and the world. CVD comprises several complex and mostly heritable …