We present the first reported cases of delayed inflammatory reactions (DIR) to hyaluronic
acid (HA) dermal fillers after exposure to the COVID-19 spike protein. DIR to HA is reported …

Hyaluronic acid (HA) is a glycosaminoglycan, a natural component of the extracellular
matrix. The identical structure of the molecule in all living organisms is its main advantage …

We present 4 cases of delayed inflammatory reaction (DIR) to facial dermal hyaluronic acid
filler rapidly following vaccination for COVID-19. All DIRs occurred after a hyaluronic acid …

Background The use of hyaluronic acid soft tissue fillers in aesthetic medicine exploded in
recent years for many reasons, including being relatively safe. Incidence of delayed …

Introduction The pandemic caused by the novel coronavirus disease 2019 (COVID‐19) has
had an unprecedented impact on the overall health and the global economy. Vaccination is …

Hyaluronic acid fillers are one of the most widely used and versatile fillers worldwide.
Although traditionally regarded as immunologically inert, many currently available products …

Background: Hyaluronidase (Hyal) can reverse complications of hyaluronic acid (HA) fillers,
which has contributed substantially to the popularity of such procedures. Still, there are …

Delayed-onset nodules (DONs) represent a poorly understood and generally neglected
group of complications. It is not a diagnosis. The underlying pathologies and their …

Objective: As the population ages, facial plastic providers must remain aware of the
treatments to prevent and reverse the external signs of aging. In the mandibular region, skin …

Introduction Soft tissue fillers are used for cosmetic and reconstructive purposes, and soft
tissue filler procedures are among the most common nonsurgical procedures in the USA …