Simple Summary Understanding the relationships between sets of regions across the brain
is critical to understanding of cognitive function. The application of graph theoretical …

Increasing evidence suggests that the neurobiological processes that govern learning and
memory can be different in males and females, but many of the specific mechanisms …

Freezing is a defensive behavior commonly examined during hippocampal-mediated fear
engram reactivation. How these cellular populations engage the brain and modulate …

Socioemotional health is positively correlated with improved cognitive and physical aging.
Despite known sex differences in socioemotional behaviors and the trajectory of aging, the …

The rodent medial prefrontal cortex (mPFC) is functionally organized across the dorsoventral
axis, where dorsal and ventral subregions promote and suppress fear, respectively. As the …

Anxiety disorders are the most prevalent mental illnesses worldwide, exhibit high heritability,
and affect twice as many women as men. To evaluate potential interactions between genetic …

The medial prefrontal cortex (mPFC) is critical to cognitive and emotional function and
underlies many neuropsychiatric disorders, including mood, fear and anxiety disorders. In …

Estrogens are potent regulators of socioemotional behavior across species. Ubiquitous in
human and animal diets, plant-derived phytoestrogens (PE) bind estrogen receptors. While …

Background In rodents, third‐trimester‐equivalent alcohol exposure (TTAE) produces
significant deficits in hippocampal‐dependent memory processes such as contextual fear …

Prior research has demonstrated genome-wide transcriptional changes related to fear and
anxiety across species, often focusing on individual brain regions or cell types. However, the …