Cancers are complex ecosystems composed of malignant cells embedded in an intricate
microenvironment made of different non-transformed cell types and extracellular matrix …

Surgical pathology workflow involves multiple labor-intensive steps, such as tissue removal,
fixation, embedding, sectioning, staining, and microscopic examination. This process is time …

Abstract Purpose: Diffusion-weighted MRI (DW-MRI) is a contrast-free modality that has
demonstrated ability to discriminate between predefined benign and malignant breast …

Hyaluronan (HA) is a key component of the dense extracellular matrix in breast cancer, and
its accumulation is associated with poor prognosis and metastasis. Pegvorhyaluronidase …

Breast cancer is the most prevalent cancer among women and the leading cause of death.
Diffusion-weighted imaging (DWI) and diffusion tensor imaging (DTI) are advanced …

Background Mean diffusivity (MD) and fractional anisotropy (FA) from diffusion MRI (dMRI)
have been associated with cell density and tissue anisotropy across tumors, but it is …

Purpose To determine whether metrics from mean apparent propagator (MAP) MRI perform
better than apparent diffusion coefficient (ADC) value in assessing the tumor-stroma ratio …

Breast cancer (BC) is characterised by a high level of heterogeneity, which is influenced by
the interaction of neoplastic cells with the tumour microenvironment. The diagnostic and …

Purpose Our study aimed to diagnose benign or malignant thyroid nodules larger than 4 cm
using quantitative diffusion-weighted imaging (DWI) analysis. Methods Eighty-two thyroid …

Background Diffusion-weighted imaging (DWI) is valuable in the screening, diagnosis, and
grading of breast lesions. However, conventional DWI (C-DWI) is prone to chemical shift and …