Perspectives of FTIR as Promising Tool for Pathogen Diagnosis, Sanitary and Welfare Monitoring in Animal Experimentation Models: A Review Based on Pertinent …

MM Neves, RF Guerra, IL de Lima, TS Arrais… - Microorganisms, 2024 - mdpi.com
Currently, there is a wide application in the literature of the use of the Fourier Transform
Infrared Spectroscopy (FTIR) technique. This basic tool has also proven to be efficient for …

[HTML][HTML] Glucocorticoids modulate neural activity via a rapid non-genomic effect on Kv2. 2 channels in the central nervous system

Y Wang, Y Zhang, J Hu, C Pan, Y Gao, Q Liu, W Xu… - Neurobiology of …, 2024 - Elsevier
Glucocorticoids are primary stress hormones that exert neuronal effects via both genomic
and non-genomic signaling pathways. However, their rapid non-genomic effects and …

Inhibiting 5‐lipoxygenase prevents skeletal muscle atrophy by targeting organogenesis signalling and insulin‐like growth factor‐1

HJ Kim, SW Kim, SH Lee, DW Jung… - Journal of Cachexia …, 2022 - Wiley Online Library
Background Skeletal muscle atrophy can occur in response to numerous factors, such as
ageing and certain medications, and produces a major socio‐economic burden. At present …

Glucocorticoids in relation to behavior, morphology, and physiology as proxy indicators for the assessment of animal welfare. A systematic mapping review

I Tiemann, LB Fijn, M Bagaria, EMA Langen… - Frontiers in Veterinary …, 2023 - frontiersin.org
Translating theoretical concepts of animal welfare into quantitative assessment protocols is
an ongoing challenge. Glucocorticoids (GCs) are frequently used as physiological measure …

Effects of the angiotensin-converting enzyme inhibitor captopril on occlusal-disharmony-induced cardiac dysfunction in mice

A Ito, Y Ohnuki, K Suita, I Matsuo, M Ishikawa… - Scientific Reports, 2023 - nature.com
Occlusal disharmony is known to affect not only the oral cavity environment, but also the
autonomic nervous system in the heart. Since the renin-angiotensin system (RAS) inhibitor …

Temperature-dependent differences in mouse gut motility are mediated by stress

A Han, C Hudson-Paz, BG Robinson, L Becker… - Lab Animal, 2024 - nature.com
Researchers have advocated elevating mouse housing temperatures from the
conventional~ 22° C to the mouse thermoneutral point of 30° C to enhance translational …

A simple and low-cost environmental enrichment program improves the welfare of Calomys callosus, a species that adapts to animal facilities

SG Klein, T Soares de Assis, GS Pereira… - Frontiers in Veterinary …, 2024 - frontiersin.org
An environmental enrichment protocol is essential for testing experimental models because
it upholds animal welfare, aligns with ethical principles in animal experimentation, and …

创伤失血性休克中糖皮质激素治疗机制的研究进展

陈锦, 穆盼盼, 郭栓柱, 李天星 - 临床急诊杂志, 2024 - whuhzzs.com
创伤失血性休克是严重创伤失血所致的低血容量性休克. 该病患者起病急, 死亡率高,
治疗难度大, 极易引起患者永久性器官功能损害或死亡, 目前迫切需要改进治疗策略 …

Circadian disturbances by altering the light–dark cycle negatively affects hematopoietic function of bone marrow in mice

H Yang, G Zhao, Y Lu, K Ma, X Gao, X She… - The FASEB …, 2024 - Wiley Online Library
Circadian rhythms in metabolically active tissues are crucial for maintaining physical health.
Circadian disturbance (CD) can cause various health issues, such as metabolic …

[PDF][PDF] Summer school for systematic reviews of animal studies: Fostering evidence-based and rigorous animal research

M Rosso, SE Doneva, DW Howells… - ALTEX-Alternatives to …, 2024 - altex.org
Dr Ineichen started by outlining the PICO framework to formulate a clear research question
for a systematic review, ie, identifying the population, the intervention, the comparison, and …