COVID-19 is a severe pandemic which has caused a devastating amount of loss in lives
around the world, and yet we still don't know how to appropriately treat this disease. We …

Autophagy plays a critical role in the dynamic growth of each cell through different
conditions. It seems that this intracellular mechanism acts as a two-edged sword against the …

Background Hypoxic microenvironment of colon cancer is associated with HIF-1α
upregulation. HIF-1α response elements are responsible for autophagy induction that …

Background Vasculogenic mimicry (VM) is characterized by the formation of tubular structure
inside the tumor stroma. It has been shown that a small fraction of cancer cells, namely …

Objective: The epidemic of T2DM is rising across the globe. Systemic inflammation plays a
pivotal role in the pathogenesis and complications of T2DM. Combination of two or more …

There is mounting evidence that the development of Alzheimer's disease (AD) interacts
extensively with immunological processes in the brain and extends beyond the neuronal …

Severe acute respiratory syndrome (SARS)-CoV-2 virus causes novel coronavirus disease
2019 (COVID-19), and there is a possible role for oxidative stress in the pathophysiology of …

Background High glucose (HG)-induced reactive oxygen species (ROS) overproduction
impairs angiogenesis that is one pivotal factor of wound healing process. Angiogenesis …

Hydroxychloroquine (HCQ), an anti-malarial drug, is suggested as a promising candidate for
the treatment of pregnancy-related disorders associated with endothelial activation, among …

Aging is a physiological process in which there is a progressive decline of function in
multiple organs such as the liver. The development of natural therapies, such as sericin, for …