Intervertebral disc degeneration (IVDD) is a pathological condition that can lead to
intractable back pain or secondary neurological deficits. There is no fundamental cure for …

Tissue repair and regeneration is a vital biological process in organisms, which is influenced
by various internal mechanisms and microenvironments. Pulsed electromagnetic fields …

Background Rats are a widely accepted preclinical model for evaluating intervertebral disc
(IVD) degeneration and regeneration. IVD morphology is commonly assessed using …

Background Degenerative disc disease, a major cause of low back pain and associated
neurological symptoms, is a global health problem with the high morbidity, workforce loss …

Raised life expectancy and aging of the general population are associated with an
increased concern for fragility fractures due to factors such as osteoporosis, reduced bone …

Rotator cuff repair failure remains common due to poor tendon healing, particularly at the
enthesis. We previously showed that pulsed electromagnetic field (PEMF) therapy improved …

Background Lumbar spinal fusion surgeries are increasing steadily due to an aging and
ever-growing population. Patients undergoing lumbar spinal fusion surgery may present …

Tendon afflictions constitute a significant share of musculoskeletal diseases and represent a
primary cause of incapacity worldwide. Unresolved/chronic inflammatory states have been …

Intervertebral disc (IVD) degeneration is regarded as a major contributor to low back pain
(LBP), causing serious economic burden on individuals and society. Unfortunately, there are …

Circadian rhythm (CR) imparts significant benefits in treating multiple diseases, such as
heart diseases and arthritis. But the CR effect on intervertebral disc degeneration (IVDD) …