Taurine supplementation as a neuroprotective strategy upon brain dysfunction in metabolic syndrome and diabetes

Z Rafiee, AM García-Serrano, JMN Duarte - Nutrients, 2022 - mdpi.com
Obesity, type 2 diabetes, and their associated comorbidities impact brain metabolism and
function and constitute risk factors for cognitive impairment. Alterations to taurine …

Chemistry and biochemistry of sulfur natural compounds: Key intermediates of metabolism and redox biology

A Francioso, A Baseggio Conrado… - Oxidative Medicine …, 2020 - Wiley Online Library
Sulfur contributes significantly to nature chemical diversity and thanks to its particular
features allows fundamental biological reactions that no other element allows. Sulfur natural …

Evolution of enzyme functionality in the flavin-containing monooxygenases

G Bailleul, G Yang, CR Nicoll, A Mattevi… - Nature …, 2023 - nature.com
Among the molecular mechanisms of adaptation in biology, enzyme functional
diversification is indispensable. By allowing organisms to expand their catalytic repertoires …

Taurine linked with healthy aging

J McGaunn, JA Baur - Science, 2023 - science.org
Taurine is an amino acid, but it contains a sulfonic acid and a b-amine that make it
structurally and chemically distinct from the more familiar amino acids that form proteins …

Comprehensive metabolic tracing reveals the origin and catabolism of cysteine in mammalian tissues and tumors

SJ Yoon, JA Combs, A Falzone, N Prieto-Farigua… - Cancer research, 2023 - AACR
Cysteine plays critical roles in cellular biosynthesis, enzyme catalysis, and redox
metabolism. The intracellular cysteine pool can be sustained by cystine uptake or de novo …

Upregulation of taurine biosynthesis and bile acid conjugation with taurine through FXR in a mouse model with human-like bile acid composition

T Miyazaki, H Ueda, T Ikegami, A Honda - Metabolites, 2023 - mdpi.com
Taurine, the end product in the sulfur-containing amino acid pathway, is conjugated with bile
acids (BAs) in the liver. The rate-limiting enzymes in both taurine synthesis and BA …

Oxidoreductase enzymes: Characteristics, applications, and challenges as a biocatalyst

Y Cárdenas‐Moreno… - Biotechnology and …, 2023 - Wiley Online Library
Oxidoreductases are enzymes with distinctive characteristics that favor their use in different
areas, such as agriculture, environmental management, medicine, and analytical chemistry …

Transcriptomic and metabolomic integration to assess the response of gilthead sea bream (Sparus aurata) exposed to the most used insect repellent: DEET.

NR Colás-Ruiz, F Courant, E Gomez… - Environmental …, 2023 - Elsevier
DEET is one of the most frequently detected insect repellents in the environment reaching
concentrations of several μg L− 1 in surface water. There is scarce information available …

Taurine, a non-proteinous essential amino acid for human body systems: an overview

N Rais, A Ved, M Shadab, R Ahmad… - Arab Gulf Journal of …, 2023 - emerald.com
Purpose Taurine (2-aminoethane sulfonic acid; C2H7NO3S) is a nonprotein sulfur-
containing β-amino acid present in nearly all mammalian tissues and the most ubiquitous …

FMO rewires metabolism to promote longevity through tryptophan and one carbon metabolism in C. elegans

HS Choi, A Bhat, MB Howington, ML Schaller… - Nature …, 2023 - nature.com
Flavin containing monooxygenases (FMOs) are promiscuous enzymes known for
metabolizing a wide range of exogenous compounds. In C. elegans, fmo-2 expression …