The coupling of aryl or vinyl halides with terminal acetylenes catalysed by palladium and
other transition metals, commonly termed as Sonogashira cross-coupling reaction, is one of …

The exploration of privileged structures in drug discovery is a rapidly emerging theme in
medicinal chemistry. These structures represent a class of molecules capable of binding to …

Now-a-days, cancer is becoming one of the major problems of public health in the world.
Pharmacology treatment is a way to increase quality and long life. Predominantly, in last …

Organic Synthesis on Solid Phase | Wiley Online Books Skip to Main Content Wiley Online
Library Wiley Online Library Search within Search term Advanced Search Citation Search …

Nonaqueous diazotization− dediazoniation of two types of aminopurine nucleoside
derivatives has been investigated. Treatment of 9-(2, 3, 5-tri-O-acetyl-β-d-ribofuranosyl)-2 …

The preparation of 6-chloro-2-iodo-9-tetrahydropyranylpurine (2), was achieved in three
high yield steps from 6-chloropurine. This derivative was then selectively substituted at C-6 …

This is the fifth review in an annual comprehensive survey series on combinatorial
chemistry. 1 There were a total of 305 small-molecule libraries published in 2001 as …

Abstract An efficient Pd (OAc) 2/Cu (Xantphos) I system for Sonogashira coupling is
disclosed. Aryl bromides/iodides and electron-poor aryl chlorides were suitable for this …

Lithiation of 6-chloro-9-(tetrahydro-2H-pyran-2-yl)-9H-purine with LiTMP, gave access to 6-
chloro-2, 8-dihalogenated purine derivatives. In particular, the 6-chloro-2, 8-diiodopurine …

A review with 1663 references to transition-metal catalyzed or mediated reactions and
functional group preparations.