Genome engineering for crop improvement and future agriculture

C Gao - Cell, 2021 - cell.com
Feeding the ever-growing population is a major challenge, especially in light of rapidly
changing climate conditions. Genome editing is set to revolutionize plant breeding and …

Precise plant genome editing using base editors and prime editors

KA Molla, S Sretenovic, KC Bansal, Y Qi - Nature Plants, 2021 - nature.com
The development of CRISPR–Cas systems has sparked a genome editing revolution in
plant genetics and breeding. These sequence-specific RNA-guided nucleases can induce …

Targeting a gene regulatory element enhances rice grain yield by decoupling panicle number and size

X Song, X Meng, H Guo, Q Cheng, Y Jing… - Nature …, 2022 - nature.com
Crop genetic improvement requires balancing complex tradeoffs caused by gene pleiotropy
and linkage drags, as exemplified by IPA1 (Ideal Plant Architecture 1), a typical pleiotropic …

Applications of CRISPR–Cas in agriculture and plant biotechnology

H Zhu, C Li, C Gao - Nature Reviews Molecular Cell Biology, 2020 - nature.com
The prokaryote-derived CRISPR–Cas genome editing technology has altered plant
molecular biology beyond all expectations. Characterized by robustness and high target …

Designing future crops: genomics-assisted breeding comes of age

RK Varshney, A Bohra, J Yu, A Graner, Q Zhang… - Trends in Plant …, 2021 - cell.com
Over the past decade, genomics-assisted breeding (GAB) has been instrumental in
harnessing the potential of modern genome resources and characterizing and exploiting …

cis-Regulatory Elements in Plant Development, Adaptation, and Evolution

AP Marand, AL Eveland, K Kaufmann… - Annual review of …, 2023 - annualreviews.org
cis-Regulatory elements encode the genomic blueprints that ensure the proper
spatiotemporal patterning of gene expression necessary for appropriate development and …

An efficient CRISPR–Cas12a promoter editing system for crop improvement

J Zhou, G Liu, Y Zhao, R Zhang, X Tang, L Li, X Jia… - Nature Plants, 2023 - nature.com
Promoter editing represents an innovative approach to introduce quantitative trait variation
(QTV) in crops. However, an efficient promoter editing system for QTV needs to be …

Cis-regulatory sequences in plants: their importance, discovery, and future challenges

RJ Schmitz, E Grotewold, M Stam - The plant cell, 2022 - academic.oup.com
The identification and characterization of cis-regulatory DNA sequences and how they
function to coordinate responses to developmental and environmental cues is of paramount …

Reap the crop wild relatives for breeding future crops

A Bohra, B Kilian, S Sivasankar, M Caccamo… - Trends in …, 2022 - cell.com
Crop wild relatives (CWRs) have provided breeders with several'game-changing'traits or
genes that have boosted crop resilience and global agricultural production. Advances in …

Enhancing grain-yield-related traits by CRISPR–Cas9 promoter editing of maize CLE genes

L Liu, J Gallagher, ED Arevalo, R Chen, T Skopelitis… - Nature Plants, 2021 - nature.com
Several yield-related traits selected during crop domestication and improvement, are
associated with increases in meristem size, which is controlled by CLE peptide signals in the …