The effect of sperm DNA fragmentation on miscarriage rates: a systematic review and meta-analysis

L Robinson, ID Gallos, SJ Conner… - Human …, 2012 - academic.oup.com
STUDY QUESTION Is there an association between high levels of sperm DNA damage and
miscarriage? SUMMARY ANSWER Miscarriage rates are positively correlated with sperm …

[HTML][HTML] Whether sperm deoxyribonucleic acid fragmentation has an effect on pregnancy and miscarriage after in vitro fertilization/intracytoplasmic sperm injection: a …

J Zhao, Q Zhang, Y Wang, Y Li - Fertility and sterility, 2014 - Elsevier
Objective To examine whether sperm DNA fragmentation has an effect on pregnancy and
miscarriage after IVF and/or intracytoplasmic sperm injection (ICSI). Design Systematic …

[HTML][HTML] Sperm DNA fragmentation: mechanisms of origin, impact on reproductive outcome, and analysis

D Sakkas, JG Alvarez - Fertility and sterility, 2010 - Elsevier
OBJECTIVE: To review the mechanisms responsible for DNA fragmentation in human
sperm, including those occurring during spermatogenesis and transport through the …

Role of sperm chromatin abnormalities and DNA damage in male infertility

A Agarwal, TM Said - Human reproduction update, 2003 - academic.oup.com
Sperm DNA integrity is essential for the accurate transmission of genetic information. It has a
highly compact and complex structure and is capable of decondensation—features that must …

Protamines and male infertility

R Oliva - Human reproduction update, 2006 - academic.oup.com
Protamines are the major nuclear sperm proteins. The human sperm nucleus contains two
types of protamine: protamine 1 (P1) encoded by a single-copy gene and the family of …

Investigation on the origin of sperm DNA fragmentation: role of apoptosis, immaturity and oxidative stress

M Muratori, L Tamburrino, S Marchiani, M Cambi… - Molecular …, 2015 - Springer
Sperm DNA fragmentation (sDF) represents a threat to male fertility, human reproduction
and the health of the offspring. The causes of sDF are still unclear, even if apoptosis …

Sperm selection in natural conception: what can we learn from Mother Nature to improve assisted reproduction outcomes?

D Sakkas, M Ramalingam, N Garrido… - Human reproduction …, 2015 - academic.oup.com
BACKGROUND In natural conception only a few sperm cells reach the ampulla or the site of
fertilization. This population is a selected group of cells since only motile cells can pass …

Insulin dependant diabetes mellitus: implications for male reproductive function

IM Agbaje, DA Rogers, CM McVicar… - Human …, 2007 - academic.oup.com
BACKGROUND Diabetes mellitus (DM) is increasing in men of reproductive age. Despite
this, the prevalence of diabetes in men attending fertility clinics is largely unknown …

Sperm DNA fragmentation decreases the pregnancy rate in an assisted reproductive technique

M Benchaib, V Braun, J Lornage, S Hadj… - Human …, 2003 - academic.oup.com
BACKGROUND: Standard sperm characteristics are poor predictors of the outcome of IVF
treatments. On the contrary, sperm genome quality has been emphasized for several years …

[HTML][HTML] The effect of sperm DNA fragmentation index on assisted reproductive technology outcomes and its relationship with semen parameters and lifestyle

H Yang, G Li, H Jin, Y Guo, Y Sun - Translational andrology and …, 2019 - ncbi.nlm.nih.gov
Background The sperm DNA fragmentation index (DFI) is widely regarded as a key measure
for assessing male fertility, but the predictive value of the DFI for outcomes of assisted …