The S100 protein family consists of 24 members functionally distributed into three main
subgroups: those that only exert intracellular regulatory effects, those with intracellular and …

Background In order to improve injury assessment of brain injuries, protein markers of
pathophysiological processes and tissue fate have been introduced in the clinic. The most …

Axonal white matter injury is believed to be a major determinant of adverse outcomes
following traumatic brain injury (TBI). We hypothesized that measurement of neurofilament …

Objective To compare neurofilament light (NfL) and tau as blood-based biomarkers for acute
sports-related concussion (SRC) and determine whether their concentrations at different …

Background S100B is considered an astrocytic in-situ marker and protein levels in
cerebrospinal fluid (CSF) or serum are often used as biomarker for astrocytic damage or …

Traumatic brain injury is a major health and socioeconomic problem that affects all societies.
However, traditional approaches to the classification of clinical severity are the subject of …

Multifaceted cellular, biochemical, and molecular monitoring of proteins and lipids is logical
as an adjunct to guiding therapies and improving outcomes in traumatic and ischemic brain …

The objective of the study was to examine how S100B, a biomarker of traumatic brain injury
(TBI), contributes to outcome prediction after adjusting for known parameters, including age …

Objectives To determine the ability and accuracy of the S-100β protein in predicting
prognosis after a moderate or severe traumatic brain injury. Design Systematic review and …

Surrogate markers have enormous potential for contributing to the diagnosis, prognosis, and
therapeutic evaluation of acute brain damage, but extensive prior study of individual …