Sepsis has been around since the dawn of time, having been described for more than 2000
years, although clinical definitions are recent. The consensus sepsis definitions have …

Objective: To review the accuracy of the pediatric consensus definition of sepsis in term
neonates and to determine the definition of neonatal sepsis used. Study Selection: The …

The first ICUs were established in the late 1950s and the specialty of critical care medicine
began to develop. Since those early days, huge improvements have been made in terms of …

Abstract Objectives The Predisposition Insult Response and Organ failure (PIRO) scoring
system has been developed for use in the emergency department (ED) to risk stratify sepsis …

Results. NLR was positively correlated with the sepsis severity prognostic scores on
admission (SOFA, rs= 0.497, p< 0.001; APACHE II, rs= 0.411, p= 0.003; SAPS II, rs= 0.445 …

Objectives To review the impact of the timeliness of antibiotic therapy on the outcome of
patients with sepsis or septic shock. Methods We searched MEDLINE, EMBASE, the …

Abstract According to the World Health Organization, post-traumatic mortality rates are still
very high and show an increasing tendency. Disorders of innate immune response that may …

Several widely used scoring systems for septic patients have been validated in an ICU
setting, and may not be appropriate for other settings like Emergency Departments (ED) or …

Introduction Sepsis is a devastating condition that is generally treated as a single disease.
Identification of meaningfully distinct clusters may improve research, treatment and …

Study objective The Third International Consensus Definitions Task Force (SEP-3) proposed
revised criteria defining sepsis and septic shock. We seek to evaluate the performance of the …