The complex genetics and biology of human temperament: a review of traditional concepts in relation to new molecular findings

CR Cloninger, KM Cloninger, I Zwir… - Translational …, 2019 - nature.com
Recent genome-wide association studies (GWAS) have shown that temperament is strongly
influenced by more than 700 genes that modulate associative conditioning by molecular …

The effect of heritability and host genetics on the gut microbiota and metabolic syndrome

MY Lim, HJ You, HS Yoon, B Kwon, JY Lee, S Lee… - Gut, 2017 - gut.bmj.com
Objective Metabolic syndrome (MetS) arises from complex interactions between host genetic
and environmental factors. Although it is now widely accepted that the gut microbiota plays a …

Sub-clinical detection of gut microbial biomarkers of obesity and type 2 diabetes

M Yassour, MY Lim, HS Yun, TL Tickle, J Sung… - Genome medicine, 2016 - Springer
Background Obesity and type 2 diabetes (T2D) are linked both with host genetics and with
environmental factors, including dysbioses of the gut microbiota. However, it is unclear …

Association of the vaginal microbiota with human papillomavirus infection in a Korean twin cohort

JE Lee, S Lee, H Lee, YM Song, K Lee, MJ Han… - PloS one, 2013 - journals.plos.org
Human papillomavirus (HPV) is the most important causative agent of cervical cancers
worldwide. However, our understanding of how the vaginal microbiota might be associated …

What is the natural measurement unit of temperament: single traits or profiles?

CR Cloninger, I Zwir - … of the Royal Society B: Biological …, 2018 - royalsocietypublishing.org
There is fundamental doubt about whether the natural unit of measurement for temperament
and personality corresponds to single traits or to multi-trait profiles that describe the …

Roseburia spp. abundance associates with alcohol consumption in humans and its administration ameliorates alcoholic fatty liver in mice

B Seo, K Jeon, S Moon, K Lee, WK Kim, H Jeong… - Cell host & …, 2020 - cell.com
Although a link between the gut microbiota and alcohol-related liver diseases (ALDs) has
previously been suggested, the causative effects of specific taxa and their functions have not …

Uncovering the complex genetics of human character

I Zwir, J Arnedo, C Del-Val, L Pulkki-Råback… - Molecular …, 2020 - nature.com
Abstract Human personality is 30–60% heritable according to twin and adoption studies.
Hundreds of genetic variants are expected to influence its complex development, but few …

Prevotella as a hub for vaginal microbiota under the influence of host genetics and their association with obesity

J Si, HJ You, J Yu, J Sung, GP Ko - Cell host & microbe, 2017 - cell.com
While the vaginal ecosystem is maintained through mutualistic relationships between the
host and the vaginal bacteria, the effect of host genetics on the vaginal microbiota has not …

Uncovering the complex genetics of human temperament

I Zwir, J Arnedo, C Del-Val, L Pulkki-Råback… - Molecular …, 2020 - nature.com
Experimental studies of learning suggest that human temperament may depend on the
molecular mechanisms for associative conditioning, which are highly conserved in animals …

Three genetic–environmental networks for human personality

I Zwir, C Del-Val, J Arnedo, L Pulkki-Råback… - Molecular …, 2021 - nature.com
Phylogenetic, developmental, and brain-imaging studies suggest that human personality is
the integrated expression of three major systems of learning and memory that regulate (1) …