Increasing evidences suggest that inflammation plays a key role in the pathogenesis of
stroke, a devastating disease second only to cardiac ischemia as a cause of death …

Object recognition (OR) and the Morris water maze (MWM) are classical tasks widely used to
assess memory parameters and deficits in rodents. Learning processes in both tasks involve …

Background. It is widely accepted that inflammation may contribute to cognitive impairment
in patients with vascular dementia (VD). Our prior clinical researches have reported that …

Inflammation and cell death play important roles in the pathogenesis of hypoxic-ischemic
brain damage (HIBD). Toll-like receptor 4 (TLR4) triggers the activation of the inflammatory …

Stroke remains the leading cause of long-term disability worldwide with significant long-term
sequelae. However, there is no highly effective treatment to enhance post-stroke recovery …

Objective and design Microglia stimulated by oxygen glucose deprivation (OGD) were
treated with quercetin to investigate the effect on oxidative stress and the inflammatory …

Neonatal hypoxic-ischemic encephalopathy (HIE) is an obstinate disease that troubles
neonatologists. At present, cognitive impairment after HIE has received increasing attention …

The role of oxytocin (OT) as a neuropeptide that modulates social behavior has been
extensively studied and reviewed, but beyond these functions, OT's adaptive functions at …

Acute ischemic stroke is a catastrophic medical condition that causes severe disability and
mortality if the sufferer escapes treatment within a stipulated timeframe. While timely …

With unknown etiology and limited treatment options, neonatal hypoxic‐ischemic brain
damage (HIBD) remains a major cause of mortality in newborns. Ferroptosis, a recently …